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@ARTICLE{Kster:126894,
      author       = {S. Köster and D. A. Weitz and R. D. Goldman and U. Aebi
                      and H. Herrmann$^*$},
      title        = {{I}ntermediate filament mechanics in vitro and in the cell:
                      from coiled coils to filaments, fibers and networks.},
      journal      = {Current opinion in cell biology},
      volume       = {32},
      issn         = {0955-0674},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2017-02922},
      pages        = {82 - 91},
      year         = {2015},
      abstract     = {Intermediate filament proteins form filaments, fibers and
                      networks both in the cytoplasm and the nucleus of metazoan
                      cells. Their general structural building plan accommodates
                      highly varying amino acid sequences to yield extended
                      dimeric α-helical coiled coils of highly conserved design.
                      These rod particles are the basic building blocks of
                      intrinsically flexible, filamentous structures that are able
                      to resist high mechanical stresses, that is, bending and
                      stretching to a considerable degree, both in vitro and in
                      the cell. Biophysical and computer modeling studies are
                      beginning to unfold detailed structural and mechanical
                      insights into these major supramolecular assemblies of cell
                      architecture, not only in the test tube but also in the
                      cellular and tissue context.},
      keywords     = {Amino Acids (NLM Chemicals)},
      cin          = {B065},
      ddc          = {570},
      cid          = {I:(DE-He78)B065-20160331},
      pnm          = {312 - Functional and structural genomics (POF3-312)},
      pid          = {G:(DE-HGF)POF3-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:25621895},
      pmc          = {pmc:PMC4355244},
      doi          = {10.1016/j.ceb.2015.01.001},
      url          = {https://inrepo02.dkfz.de/record/126894},
}