%0 Journal Article
%A Merz, M.
%A Hielscher, T.
%A Wagner, B.
%A Sauer, S.
%A Shah, S.
%A Raab, M. S.
%A Jauch, A.
%A Neben, K.
%A Hose, D.
%A Egerer, G.
%A Weber, M. A.
%A Delorme, S.
%A Goldschmidt, H.
%A Hillengass, Jens
%T Predictive value of longitudinal whole-body magnetic resonance imaging in patients with smoldering multiple myeloma.
%J Leukemia
%V 28
%N 9
%@ 1476-5551
%C Basingstoke
%I Nature Publ. Group
%M DKFZ-2017-03970
%P 1902 - 1908
%D 2014
%X Previous studies demonstrated the relevance of focal lesions (FL) in whole-body magnetic resonance imaging (wb-MRI) at the initial workup of patients with smoldering multiple myeloma (SMM). The aim of this study was to assess the effects of longitudinal wb-MRIs on progression into multiple myeloma (MM). Sixty-three patients with SMM were analyzed who received at least two wb-MRIs for follow-up before progression into MM. Radiological progressive disease (MRI-PD) was defined as detection of new FL or increase in diameter of existing FL and a novel or progressive diffuse infiltration. Radiological stable disease (MRI-SD) was defined by no change compared with the prior MRI. Patients were followed-up every 3-6 months, including a serological and clinical evaluation. One Hundred and eighty-two wb-MRIs were analyzed. MRI-PD occurred in 31 patients (49
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:24535407
%R 10.1038/leu.2014.75
%U https://inrepo02.dkfz.de/record/127948