TY  - JOUR
AU  - Merz, M.
AU  - Hielscher, T.
AU  - Wagner, B.
AU  - Sauer, S.
AU  - Shah, S.
AU  - Raab, M. S.
AU  - Jauch, A.
AU  - Neben, K.
AU  - Hose, D.
AU  - Egerer, G.
AU  - Weber, M. A.
AU  - Delorme, S.
AU  - Goldschmidt, H.
AU  - Hillengass, Jens
TI  - Predictive value of longitudinal whole-body magnetic resonance imaging in patients with smoldering multiple myeloma.
JO  - Leukemia
VL  - 28
IS  - 9
SN  - 1476-5551
CY  - Basingstoke
PB  - Nature Publ. Group
M1  - DKFZ-2017-03970
SP  - 1902 - 1908
PY  - 2014
AB  - Previous studies demonstrated the relevance of focal lesions (FL) in whole-body magnetic resonance imaging (wb-MRI) at the initial workup of patients with smoldering multiple myeloma (SMM). The aim of this study was to assess the effects of longitudinal wb-MRIs on progression into multiple myeloma (MM). Sixty-three patients with SMM were analyzed who received at least two wb-MRIs for follow-up before progression into MM. Radiological progressive disease (MRI-PD) was defined as detection of new FL or increase in diameter of existing FL and a novel or progressive diffuse infiltration. Radiological stable disease (MRI-SD) was defined by no change compared with the prior MRI. Patients were followed-up every 3-6 months, including a serological and clinical evaluation. One Hundred and eighty-two wb-MRIs were analyzed. MRI-PD occurred in 31 patients (49
LB  - PUB:(DE-HGF)16
C6  - pmid:24535407
DO  - DOI:10.1038/leu.2014.75
UR  - https://inrepo02.dkfz.de/record/127948
ER  -