TY  - JOUR
AU  - Wieser, Hans-Peter
AU  - Cisternas, Eduardo
AU  - Wahl, Niklas
AU  - Ulrich, Silke
AU  - Stadler, Alexander
AU  - Mescher, Henning
AU  - Müller, Lucas-Raphael
AU  - Klinge, Thomas
AU  - Gabrys, Hubert
AU  - Burigo, Lucas Norberto
AU  - Mairani, Andrea
AU  - Ecker, Swantje
AU  - Ackermann, Benjamin
AU  - Ellerbrock, Malte
AU  - Parodi, Katia
AU  - Jäkel, Oliver
AU  - Bangert, Mark
TI  - Development of the open-source dose calculation and optimization toolkit matRad.
JO  - Medical physics
VL  - 44
IS  - 6
SN  - 0094-2405
CY  - New York, NY
M1  - DKFZ-2017-04248
SP  - 2556 - 2568
PY  - 2017
AB  - We report on the development of the open-source cross-platform radiation treatment planning toolkit matRad and its comparison against validated treatment planning systems. The toolkit enables three-dimensional intensity-modulated radiation therapy treatment planning for photons, scanned protons and scanned carbon ions.matRad is entirely written in Matlab and is freely available online. It re-implements well-established algorithms employing a modular and sequential software design to model the entire treatment planning workflow. It comprises core functionalities to import DICOM data, to calculate and optimize dose as well as a graphical user interface for visualization. matRad dose calculation algorithms (for carbon ions this also includes the computation of the relative biological effect) are compared against dose calculation results originating from clinically approved treatment planning systems.We observe three-dimensional γ-analysis pass rates ≥ 99.67
LB  - PUB:(DE-HGF)16
C6  - pmid:28370020
DO  - DOI:10.1002/mp.12251
UR  - https://inrepo02.dkfz.de/record/128231
ER  -