Journal Article

DKFZ-2017-04410

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png tRNAs: new tricks from old dogs.

Stoecklin, G. (First author)DKFZ* ; Diederichs, S. (Last author)DKFZ*

2014
EMBO Press Heidelberg

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Please use a persistent id in citations: doi:10.15252/embj.201489634

Abstract: tRNA biology has lately seen a revival with the discovery of tRNA cleavage products as mediators of stress responses. In this issue of The EMBO Journal, Blanco et al now report that tRNA methylation, by protecting from cleavage, is relevant for normal brain development. The versatility of tRNA is further emphasized by a recent study in Cell that uncovered differential expression of tRNAs as a means to accustom codon usage bias to the needs in proliferating versus differentiating cells.

Keyword(s): RNA, Transfer ; Methyltransferases ; Misu protein, mouse ; NSUN2 protein, human

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Contributing Institute(s):

1. Posttranskriptionelle Genregulation (A200)
2. RNA-Biologie und Krebs (B150)

Research Program(s):

1. 312 - Functional and structural genomics (POF3-312) (POF3-312)

Appears in the scientific report 2014

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Database coverage:
; BIOSIS Previews ; Current Contents - Life Sciences ; Ebsco Academic Search ; IF >= 5 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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