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@ARTICLE{UgarteUribe:128449,
      author       = {B. Ugarte-Uribe and A. J. García-Sáez$^*$},
      title        = {{M}embranes in motion: mitochondrial dynamics and their
                      role in apoptosis.},
      journal      = {Biological chemistry},
      volume       = {395},
      number       = {3},
      issn         = {1437-4315},
      address      = {Berlin [u.a.]},
      publisher    = {de Gruyter},
      reportid     = {DKFZ-2017-04465},
      pages        = {297-311},
      year         = {2014},
      abstract     = {Mitochondrial dynamics is crucial for cell survival,
                      development and homeostasis and impairment of these
                      functions leads to neurologic disorders and metabolic
                      diseases. The key components of mitochondrial dynamics have
                      been identified. Mitofusins and OPA1 mediate mitochondrial
                      fusion, whereas Drp1 is responsible for mitochondrial
                      fission. In addition, an interplay between the proteins of
                      the mitochondrial fission/fusion machinery and the Bcl-2
                      proteins, essential mediators in apoptosis, has been also
                      described. Here, we review the molecular mechanisms
                      regarding mitochondrial dynamics together with their role in
                      apoptosis.},
      cin          = {B160},
      ddc          = {540},
      cid          = {I:(DE-He78)B160-20160331},
      pnm          = {312 - Functional and structural genomics (POF3-312)},
      pid          = {G:(DE-HGF)POF3-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:24184992},
      doi          = {10.1515/hsz-2013-0234},
      url          = {https://inrepo02.dkfz.de/record/128449},
}