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@ARTICLE{Engeland:128621,
      author       = {C. Engeland$^*$ and S. Bossow$^*$ and A. W. Hudacek and B.
                      Hoyler$^*$ and J. Förster$^*$ and R. Veinalde$^*$ and D.
                      Jäger$^*$ and R. Cattaneo and G. Ungerechts$^*$ and C.
                      Springfeld},
      title        = {{A} {T}upaia paramyxovirus vector system for targeting and
                      transgene expression.},
      journal      = {Journal of general virology},
      volume       = {98},
      number       = {9},
      issn         = {1465-2099},
      address      = {Reading},
      publisher    = {Soc.},
      reportid     = {DKFZ-2017-04637},
      pages        = {2248 - 2257},
      year         = {2017},
      abstract     = {Viruses from the diverse family of Paramyxoviridae include
                      important pathogens and are applied in gene therapy and for
                      cancer treatment. The Tupaia paramyxovirus (TPMV), isolated
                      from the kidney of a tree shrew, does not infect human cells
                      and neutralizing antibodies against other Paramyxoviridae do
                      not cross-react with TPMV. Here, we present a vector system
                      for de novo generation of infectious TPMV that allows for
                      insertion of additional genes as well as targeting using
                      antibody single-chain variable fragments. We show that the
                      recombinant TPMV specifically infect cells expressing the
                      targeted receptor and replicate in human cells. This vector
                      system provides a valuable tool for both basic research and
                      therapeutic applications.},
      cin          = {G100 / G010},
      ddc          = {570},
      cid          = {I:(DE-He78)G100-20160331 / I:(DE-He78)G010-20160331},
      pnm          = {317 - Translational cancer research (POF3-317)},
      pid          = {G:(DE-HGF)POF3-317},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28809150},
      doi          = {10.1099/jgv.0.000887},
      url          = {https://inrepo02.dkfz.de/record/128621},
}