% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Klein:132488,
      author       = {A. P. Klein and B. M. Wolpin and H. A. Risch and R. Z.
                      Stolzenberg-Solomon and E. Mocci and M. Zhang and F. Canzian
                      and E. J. Childs and J. W. Hoskins and A. Jermusyk and J.
                      Zhong and F. Chen and D. Albanes and G. Andreotti and A. A.
                      Arslan and A. Babic and W. R. Bamlet and L. Beane-Freeman
                      and S. I. Berndt and A. Blackford and M. Borges and A.
                      Borgida and P. M. Bracci and L. Brais and P. Brennan and H.
                      Brenner$^*$ and B. Bueno-de-Mesquita and J. Buring and D.
                      Campa and G. Capurso and G. M. Cavestro and K. G. Chaffee
                      and C. C. Chung and S. Cleary and M. Cotterchio and F. Dijk
                      and E. J. Duell and L. Foretova and C. Fuchs and N. Funel
                      and S. Gallinger and J. M. M Gaziano and M. Gazouli and G.
                      G. Giles and E. Giovannucci and M. Goggins and G. E. Goodman
                      and P. J. Goodman and T. Hackert and C. Haiman and P. Hartge
                      and M. Hasan and P. Hegyi and K. J. Helzlsouer and J. Herman
                      and I. Holcatova and E. A. Holly and R. Hoover and R. J.
                      Hung and E. J. Jacobs and K. Jamroziak and V. Janout and R.
                      Kaaks$^*$ and K.-T. Khaw and E. A. Klein and M. Kogevinas
                      and C. Kooperberg and M. H. Kulke and J. Kupcinskas and R.
                      J. Kurtz and D. Laheru and S. Landi and R. T. Lawlor and
                      I.-M. Lee and L. LeMarchand and L. Lu and N. Malats and A.
                      Mambrini and S. Mannisto and R. L. Milne and B.
                      Mohelníková-Duchoňová and R. E. Neale and J. P.
                      Neoptolemos and A. L. Oberg and S. H. Olson and I. Orlow and
                      C. Pasquali and A. V. Patel and U. Peters and R. Pezzilli
                      and M. Porta and F. X. Real and N. Rothman and G. Scelo and
                      H. D. Sesso and G. Severi and X.-O. Shu and D. Silverman and
                      J. P. Smith and P. Soucek and M. Sund and R.
                      Talar-Wojnarowska and F. Tavano and M. D. Thornquist and G.
                      S. Tobias and S. K. Van Den Eeden and Y. Vashist and K.
                      Visvanathan and P. Vodicka and J. Wactawski-Wende and Z.
                      Wang and N. Wentzensen and E. White and H. Yu and K. Yu and
                      A. Zeleniuch-Jacquotte and W. Zheng and P. Kraft and D. Li
                      and S. Chanock and O. Obazee$^*$ and G. M. Petersen and L.
                      T. Amundadottir},
      title        = {{G}enome-wide meta-analysis identifies five new
                      susceptibility loci for pancreatic cancer.},
      journal      = {Nature Communications},
      volume       = {9},
      number       = {1},
      issn         = {2041-1723},
      address      = {London},
      publisher    = {Nature Publishing Group},
      reportid     = {DKFZ-2018-00175},
      pages        = {556},
      year         = {2018},
      abstract     = {In 2020, 146,063 deaths due to pancreatic cancer are
                      estimated to occur in Europe and the United States combined.
                      To identify common susceptibility alleles, we performed the
                      largest pancreatic cancer GWAS to date, including 9040
                      patients and 12,496 controls of European ancestry from the
                      Pancreatic Cancer Cohort Consortium (PanScan) and the
                      Pancreatic Cancer Case-Control Consortium (PanC4). Here, we
                      find significant evidence of a novel association at
                      rs78417682 (7p12/TNS3, P = 4.35 × 10-8).
                      Replication of 10 promising signals in up to 2737 patients
                      and 4752 controls from the PANcreatic Disease ReseArch
                      (PANDoRA) consortium yields new genome-wide significant
                      loci: rs13303010 at 1p36.33 (NOC2L,
                      P = 8.36 × 10-14), rs2941471 at 8q21.11 (HNF4G,
                      P = 6.60 × 10-10), rs4795218 at 17q12 (HNF1B,
                      P = 1.32 × 10-8), and rs1517037 at 18q21.32 (GRP,
                      P = 3.28 × 10-8). rs78417682 is not statistically
                      significantly associated with pancreatic cancer in PANDoRA.
                      Expression quantitative trait locus analysis in three
                      independent pancreatic data sets provides molecular support
                      of NOC2L as a pancreatic cancer susceptibility gene.},
      cin          = {C070 / G110 / C020 / C055},
      ddc          = {500},
      cid          = {I:(DE-He78)C070-20160331 / I:(DE-He78)G110-20160331 /
                      I:(DE-He78)C020-20160331 / I:(DE-He78)C055-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29422604},
      pmc          = {pmc:PMC5805680},
      doi          = {10.1038/s41467-018-02942-5},
      url          = {https://inrepo02.dkfz.de/record/132488},
}