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@ARTICLE{Korzowski:132490,
      author       = {A. Korzowski$^*$ and P. Bachert$^*$},
      title        = {{H}igh-resolution31{P} echo-planar spectroscopic imaging in
                      vivo at 7{T}.},
      journal      = {Magnetic resonance in medicine},
      volume       = {79},
      number       = {3},
      issn         = {0740-3194},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {DKFZ-2018-00177},
      pages        = {1251 - 1259},
      year         = {2018},
      abstract     = {Conventional31P chemical shift imaging is time-consuming
                      and yields only limited spatial resolution. The purpose of
                      this study was to demonstrate feasibility of31P echo-planar
                      spectroscopic imaging (EPSI) in vivo at 7T.A 3D31P EPSI
                      sequence with trapezoidal-shaped gradient pulses was
                      implemented on a 7T MR scanner. To increase spectral width
                      with reduced demand on gradient performance, a multishot
                      approach was chosen. Acquisition weighting and31P-{1H}
                      double resonance for nuclear Overhauser signal enhancement
                      were applied to increase sensitivity.3D31P-{1H} EPSI data
                      from model solution and from human calf muscle and brain
                      were obtained from voxels with effective sizes of 4.1 to
                      16.2 cm3in measurement times of approximately 10 min.
                      Individual spectra showed well-resolved resonances of
                      endogenous31P-metabolites without artifacts. Volumetric
                      high-resolution31P-metabolite maps in vivo showed metabolic
                      heterogeneity of different tissues.In vivo31P EPSI at 7T
                      yields high-quality metabolic images. The proposed multishot
                      EPSI technique reduces the measurement times for acquisition
                      of volumetric high-resolution maps of31P-metabolites or
                      intracellular pH in human studies. Magn Reson Med
                      79:1251-1259, 2018. © 2017 International Society for
                      Magnetic Resonance in Medicine.},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28639310},
      doi          = {10.1002/mrm.26785},
      url          = {https://inrepo02.dkfz.de/record/132490},
}