guest ::
| Home > Publications database > The DNA damage-induced cell death response: a roadmap to kill cancer cells. > print |
| Home > Publications database > The DNA damage-induced cell death response: a roadmap to kill cancer cells. > print |
| 001 | 132584 | ||
| 005 | 20240228143509.0 | ||
| 024 | 7 | _ | |a 10.1007/s00018-016-2130-4 |2 doi |
| 024 | 7 | _ | |a pmid:26791483 |2 pmid |
| 024 | 7 | _ | |a 0014-4754 |2 ISSN |
| 024 | 7 | _ | |a 1420-682X |2 ISSN |
| 024 | 7 | _ | |a 1420-9071 |2 ISSN |
| 024 | 7 | _ | |a altmetric:17894048 |2 altmetric |
| 037 | _ | _ | |a DKFZ-2018-00250 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Matt, Sonja |0 P:(DE-He78)ce86d7d02a229acfaca4b63f01a1171b |b 0 |e First author |u dkfz |
| 245 | _ | _ | |a The DNA damage-induced cell death response: a roadmap to kill cancer cells. |
| 260 | _ | _ | |a Basel |c 2016 |b Birkhäuser |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1521121817_3407 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a review, ZMBH Allianz |
| 520 | _ | _ | |a Upon massive DNA damage cells fail to undergo productive DNA repair and trigger the cell death response. Resistance to cell death is linked to cellular transformation and carcinogenesis as well as radio- and chemoresistance, making the underlying signaling pathways a promising target for therapeutic intervention. Diverse DNA damage-induced cell death pathways are operative in mammalian cells and finally culminate in the induction of programmed cell death via activation of apoptosis or necroptosis. These signaling routes affect nuclear, mitochondria- and plasma membrane-associated key molecules to activate the apoptotic or necroptotic response. In this review, we highlight the main signaling pathways, molecular players and mechanisms guiding the DNA damage-induced cell death response. |
| 536 | _ | _ | |a 311 - Signalling pathways, cell and tumor biology (POF3-311) |0 G:(DE-HGF)POF3-311 |c POF3-311 |f POF III |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
| 700 | 1 | _ | |a Hofmann, Thomas |0 P:(DE-He78)99ae95278bd95e30462a4fb2d12026c6 |b 1 |e Last author |u dkfz |
| 773 | _ | _ | |a 10.1007/s00018-016-2130-4 |g Vol. 73, no. 15, p. 2829 - 2850 |0 PERI:(DE-600)1458497-9 |n 15 |p 2829 - 2850 |t Cellular and molecular life sciences |v 73 |y 2016 |x 1420-9071 |
| 909 | C | O | |o oai:inrepo02.dkfz.de:132584 |p VDB |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 0 |6 P:(DE-He78)ce86d7d02a229acfaca4b63f01a1171b |
| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 1 |6 P:(DE-He78)99ae95278bd95e30462a4fb2d12026c6 |
| 913 | 1 | _ | |a DE-HGF |l Krebsforschung |1 G:(DE-HGF)POF3-310 |0 G:(DE-HGF)POF3-311 |2 G:(DE-HGF)POF3-300 |v Signalling pathways, cell and tumor biology |x 0 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF3 |b Gesundheit |
| 914 | 1 | _ | |y 2016 |
| 915 | _ | _ | |a Nationallizenz |0 StatID:(DE-HGF)0420 |2 StatID |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Thomson Reuters Master Journal List |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0110 |2 StatID |b Science Citation Index |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1120 |2 StatID |b BIOSIS Reviews Reports And Meetings |
| 920 | 1 | _ | |0 I:(DE-He78)A210-20160331 |k A210 |l Zelluläre Seneszenz |x 0 |
| 920 | 1 | _ | |0 I:(DE-He78)A130-20160331 |k A130 |l Epigenetik |x 1 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-He78)A210-20160331 |
| 980 | _ | _ | |a I:(DE-He78)A130-20160331 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|