%0 Journal Article
%A Niesporek, Sebastian
%A Umathum, Reiner
%A Lommen, Jonathan
%A Behl, Nicolas
%A Paech, Daniel
%A Bachert, Peter
%A Ladd, Mark
%A Nagel, Armin
%T Reproducibility of CMRO2determination using dynamic17O MRI.
%J Magnetic resonance in medicine
%V 79
%N 6
%@ 0740-3194
%C New York, NY [u.a.]
%I Wiley-Liss
%M DKFZ-2018-00323
%P 2923 - 2934
%D 2018
%X To assess the reproducibility of17O MRI-based determination of the cerebral metabolic rate of oxygen consumption (CMRO2) in healthy volunteers. To assess the influence of image acquisition and reconstruction parameters on dynamic quantification of functional parameters such as CMRO2.Dynamic17O MRI data were simulated and used to investigate influences of temporal resolution (Δt) and partial volume correction (PVC) on the determination of CMRO2. Three healthy volunteers were examined in two separate examinations. In vivo17O MRI measurements were conducted with a nominal spatial resolution of (7.5 mm)3using a density-adapted radial sequence with golden angle acquisition scheme. In each measurement, 4.0 ± 0.1 L of 70
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:29030876
%R 10.1002/mrm.26952
%U https://inrepo02.dkfz.de/record/132663