TY  - JOUR
AU  - Niesporek, Sebastian
AU  - Umathum, Reiner
AU  - Lommen, Jonathan
AU  - Behl, Nicolas
AU  - Paech, Daniel
AU  - Bachert, Peter
AU  - Ladd, Mark
AU  - Nagel, Armin
TI  - Reproducibility of CMRO2determination using dynamic17O MRI.
JO  - Magnetic resonance in medicine
VL  - 79
IS  - 6
SN  - 0740-3194
CY  - New York, NY [u.a.]
PB  - Wiley-Liss
M1  - DKFZ-2018-00323
SP  - 2923 - 2934
PY  - 2018
AB  - To assess the reproducibility of17O MRI-based determination of the cerebral metabolic rate of oxygen consumption (CMRO2) in healthy volunteers. To assess the influence of image acquisition and reconstruction parameters on dynamic quantification of functional parameters such as CMRO2.Dynamic17O MRI data were simulated and used to investigate influences of temporal resolution (Δt) and partial volume correction (PVC) on the determination of CMRO2. Three healthy volunteers were examined in two separate examinations. In vivo17O MRI measurements were conducted with a nominal spatial resolution of (7.5 mm)3using a density-adapted radial sequence with golden angle acquisition scheme. In each measurement, 4.0 ± 0.1 L of 70
LB  - PUB:(DE-HGF)16
C6  - pmid:29030876
DO  - DOI:10.1002/mrm.26952
UR  - https://inrepo02.dkfz.de/record/132663
ER  -