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@ARTICLE{Vijayakrishnan:132868,
      author       = {J. Vijayakrishnan and J. Studd and P. Broderick and B.
                      Kinnersley and A. Holroyd and P. J. Law and R. Kumar$^*$ and
                      J. M. Allan and C. J. Harrison and A. V. Moorman and A. Vora
                      and E. Roman and S. Rachakonda$^*$ and S. E. Kinsey and E.
                      Sheridan and P. D. Thompson and J. A. Irving and R. Koehler
                      and P. Hoffmann and M. M. Nöthen and S. Heilmann-Heimbach
                      and K.-H. Jöckel and D. F. Easton and P. D. P. Pharaoh and
                      A. M. Dunning and J. Peto and F. Canzian$^*$ and A. Swerdlow
                      and R. A. Eeles and Z. Kote-Jarai and K. Muir and N.
                      Pashayan and M. Greaves and M. Zimmerman and C. R. Bartram
                      and M. Schrappe and M. Stanulla and K. Hemminki$^*$ and R.
                      S. Houlston and B. E. Henderson and C. A. Haiman and S.
                      Benlloch and F. R. Schumacher and A. A. A. Olama and S. I.
                      Berndt and D. V. Conti and F. Wiklund and S. Chanock and V.
                      L. Stevens and C. M. Tangen and J. Batra and J. Clements and
                      H. Gronberg and J. Schleutker and D. Albanes and S.
                      Weinstein and A. Wolk and C. West and L. Mucci and G.
                      Cancel-Tassin and S. Koutros and K. D. Sorensen and L.
                      Maehle and D. E. Neal and R. C. Travis and R. J. Hamilton
                      and S. A. Ingles and B. Rosenstein and Y.-J. Lu and G. G.
                      Giles and A. S. Kibel and A. Vega and M. Kogevinas and K. L.
                      Penney and J. Y. Park and J. L. Stanford and C. Cybulski and
                      B. G. Nordestgaard and H. Brenner$^*$ and C. Maier and J.
                      Kim and E. M. John and M. R. Teixeira and S. L. Neuhausen
                      and K. De Ruyck and A. Razack and L. F. Newcomb and D.
                      Lessel and R. Kaneva and N. Usmani and F. Claessens and P.
                      A. Townsend and M. G. Dominguez and M. J. Roobol and F.
                      Menegaux},
      collaboration = {P. Consortium},
      title        = {{G}enome-wide association study identifies susceptibility
                      loci for {B}-cell childhood acute lymphoblastic leukemia.},
      journal      = {Nature Communications},
      volume       = {9},
      number       = {1},
      issn         = {2041-1723},
      address      = {London},
      publisher    = {Nature Publishing Group},
      reportid     = {DKFZ-2018-00511},
      pages        = {1340},
      year         = {2018},
      abstract     = {Genome-wide association studies (GWAS) have advanced our
                      understanding of susceptibility to B-cell precursor acute
                      lymphoblastic leukemia (BCP-ALL); however, much of the
                      heritable risk remains unidentified. Here, we perform a GWAS
                      and conduct a meta-analysis with two existing GWAS, totaling
                      2442 cases and 14,609 controls. We identify risk loci for
                      BCP-ALL at 8q24.21 (rs28665337, P = 3.86 × 10-9,
                      odds ratio (OR) = 1.34) and for ETV6-RUNX1
                      fusion-positive BCP-ALL at 2q22.3 (rs17481869,
                      P = 3.20 × 10-8, OR = 2.14). Our findings
                      provide further insights into genetic susceptibility to ALL
                      and its biology.},
      cin          = {C050 / C055 / C070 / G110},
      ddc          = {500},
      cid          = {I:(DE-He78)C050-20160331 / I:(DE-He78)C055-20160331 /
                      I:(DE-He78)C070-20160331 / I:(DE-He78)G110-20160331},
      pnm          = {317 - Translational cancer research (POF3-317)},
      pid          = {G:(DE-HGF)POF3-317},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29632299},
      pmc          = {pmc:PMC5890276},
      doi          = {10.1038/s41467-018-03178-z},
      url          = {https://inrepo02.dkfz.de/record/132868},
}