Journal Article (Review Article) DKFZ-2018-01262

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The Evolving Landscape of Brain Metastasis.

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2018
Elsevier Amsterdam

Trends in cancer 4(3), 176 - 196 () [10.1016/j.trecan.2018.01.003]
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Abstract: Metastasis, involving the spread of systemic cancer to the brain, results in neurologic disability and death. Current treatments are largely palliative in nature; improved therapeutic approaches represent an unmet clinical need. However, recent experimental and clinical advances challenge the bleak long-term outcome of this disease. Encompassing key recent findings in epidemiology, genetics, microenvironment, leptomeningeal disease, neurocognition, targeted therapy, immunotherapy, and prophylaxis, we review preclinical and clinical studies to provide a comprehensive picture of contemporary research and the management of secondary brain tumors.

Classification:

Contributing Institute(s):
  1. KKE Neuroonkologie (G370)
Research Program(s):
  1. 317 - Translational cancer research (POF3-317) (POF3-317)

Appears in the scientific report 2018
Database coverage:
Medline ; SCOPUS
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 Record created 2018-08-30, last modified 2024-02-29



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