%0 Journal Article
%A Matt, Sonja
%A Hofmann, Thomas
%T Crosstalk between p53 modifiers at PML bodies.
%J Molecular & cellular oncology
%V 5
%N 3
%@ 2372-3556
%C London
%I Taylor & Francis
%M DKFZ-2018-01567
%P e1074335 -
%D 2018
%X Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage. Regulation of p53 activity by post-translational modifications has been linked to promyelocytic leukemia nuclear bodies (PML-NBs), where p53 encounters many of its regulators. Recent evidence implies that crosstalk between p53 regulators at the PML-NB shapes post-translational modifications and function of p53.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30250876
%2 pmc:PMC6150047
%R 10.1080/23723556.2015.1074335
%U https://inrepo02.dkfz.de/record/137690