TY  - JOUR
AU  - Matt, Sonja
AU  - Hofmann, Thomas
TI  - Crosstalk between p53 modifiers at PML bodies.
JO  - Molecular & cellular oncology
VL  - 5
IS  - 3
SN  - 2372-3556
CY  - London
PB  - Taylor & Francis
M1  - DKFZ-2018-01567
SP  - e1074335 -
PY  - 2018
AB  - Tumor protein p53 (TP53, best known as p53), the most frequently mutated tumor suppressor in cancer, plays a central role in cell fate decisions induced by DNA damage. Regulation of p53 activity by post-translational modifications has been linked to promyelocytic leukemia nuclear bodies (PML-NBs), where p53 encounters many of its regulators. Recent evidence implies that crosstalk between p53 regulators at the PML-NB shapes post-translational modifications and function of p53.
LB  - PUB:(DE-HGF)16
C6  - pmid:30250876
C2  - pmc:PMC6150047
DO  - DOI:10.1080/23723556.2015.1074335
UR  - https://inrepo02.dkfz.de/record/137690
ER  -