TY  - JOUR
AU  - Lipka, Daniel
AU  - Lutsik, Pavlo
AU  - Plass, Christoph
TI  - From Basic Knowledge to Effective Therapies.
JO  - Cancer cell
VL  - 34
IS  - 6
SN  - 1535-6108
CY  - New York, NY
PB  - Elsevier
M1  - DKFZ-2019-00192
SP  - 871 - 873
PY  - 2018
AB  - In this issue of Cancer Cell, Ott et al. use integrative analysis of histone ChIP-seq and ATAC-seq to describe enhancer-based regulatory circuits in chronic lymphocytic leukemia. This work identified and validated transcription factor PAX5 as main driver of an oncogenic circuitry, which can be disrupted by BET bromodomain inhibition.
LB  - PUB:(DE-HGF)16
C6  - pmid:30537508
DO  - DOI:10.1016/j.ccell.2018.11.013
UR  - https://inrepo02.dkfz.de/record/142473
ER  -