Journal Article

DKFZ-2019-00192

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png From Basic Knowledge to Effective Therapies.

Lipka, D. (First author)DKFZ* ; Lutsik, P.DKFZ* ; Plass, C. (Last author)DKFZ*

2018
Elsevier New York, NY

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Please use a persistent id in citations: doi:10.1016/j.ccell.2018.11.013

Abstract: In this issue of Cancer Cell, Ott et al. use integrative analysis of histone ChIP-seq and ATAC-seq to describe enhancer-based regulatory circuits in chronic lymphocytic leukemia. This work identified and validated transcription factor PAX5 as main driver of an oncogenic circuitry, which can be disrupted by BET bromodomain inhibition.

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Contributing Institute(s):

1. Epigenomik und Krebsrisikofaktoren (C010)

Research Program(s):

1. 313 - Cancer risk factors and prevention (POF3-313) (POF3-313)

Appears in the scientific report 2018

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Database coverage:
; BIOSIS Previews ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; Ebsco Academic Search ; IF >= 20 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Web of Science Core Collection

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