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@ARTICLE{Lipka:142473,
author = {D. Lipka$^*$ and P. Lutsik$^*$ and C. Plass$^*$},
title = {{F}rom {B}asic {K}nowledge to {E}ffective {T}herapies.},
journal = {Cancer cell},
volume = {34},
number = {6},
issn = {1535-6108},
address = {New York, NY},
publisher = {Elsevier},
reportid = {DKFZ-2019-00192},
pages = {871 - 873},
year = {2018},
abstract = {In this issue of Cancer Cell, Ott et al. use integrative
analysis of histone ChIP-seq and ATAC-seq to describe
enhancer-based regulatory circuits in chronic lymphocytic
leukemia. This work identified and validated transcription
factor PAX5 as main driver of an oncogenic circuitry, which
can be disrupted by BET bromodomain inhibition.},
cin = {C010},
ddc = {610},
cid = {I:(DE-He78)C010-20160331},
pnm = {313 - Cancer risk factors and prevention (POF3-313)},
pid = {G:(DE-HGF)POF3-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30537508},
doi = {10.1016/j.ccell.2018.11.013},
url = {https://inrepo02.dkfz.de/record/142473},
}