% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Cirera:143933,
      author       = {L. Cirera and J. M. Huerta and M. D. Chirlaque and K.
                      Overvad and M. Lindström and S. Regnér and A. Tjønneland
                      and M.-C. Boutron-Ruault and V. Rebours and G. Fagherazzi
                      and V. A. Katzke$^*$ and H. Boeing and E. Peppa and A.
                      Trichopoulou and E. Valanou and D. Palli and S. Grioni and
                      S. Panico and R. Tumino and F. Ricceri and C. van Gils and
                      R. C. H. Vermeulen and G. Skeie and T. Braaten and E.
                      Weiderpass and S. Merino and M. J. Sánchez and N.
                      Larrañaga and E. Ardanaz and M. Sund and K.-T. Khaw and T.
                      J. Key and M. Jenab and S. Naudin and N. Murphy and D. Aune
                      and H. Ward and E. Riboli and B. Bueno-de-Mesquita and C.
                      Navarro and E. J. Duell},
      title        = {{S}ocioeconomic {E}ffect of {E}ducation on {P}ancreatic
                      {C}ancer {R}isk in {W}estern {E}urope: {A}n {U}pdate on the
                      {EPIC} {C}ohorts {S}tudy.},
      journal      = {Cancer epidemiology, biomarkers $\&$ prevention},
      volume       = {28},
      number       = {6},
      issn         = {1538-7755},
      address      = {Philadelphia, Pa.},
      publisher    = {AACR},
      reportid     = {DKFZ-2019-01490},
      pages        = {1089 - 1092},
      year         = {2019},
      abstract     = {To analyze the potential effect of social inequality on
                      pancreatic cancer risk in Western Europe, by reassessing the
                      association within the European Prospective Investigation
                      into Cancer and Nutrition (EPIC) Study, including a larger
                      number of cases and an extended follow-up.Data on highest
                      education attained were gathered for 459,170 participants
                      $(70\%$ women) from 10 European countries. A relative index
                      of inequality (RII) based on adult education was calculated
                      for comparability across countries and generations. Cox
                      regression models were applied to estimate relative
                      inequality in pancreatic cancer risk, stratifying by age,
                      gender, and center, and adjusting for known pancreatic
                      cancer risk factors.A total of 1,223 incident pancreatic
                      cancer cases were included after a mean follow-up of 13.9
                      (±4.0) years. An inverse social trend was found in models
                      adjusted for age, sex, and center for both sexes [HR of RII,
                      1.27; $95\%$ confidence interval (CI), 1.02-1.59], which was
                      also significant among women (HR, 1.42; $95\%$ CI,
                      1.05-1.92). Further adjusting by smoking intensity, alcohol
                      consumption, body mass index, prevalent diabetes, and
                      physical activity led to an attenuation of the RII risk and
                      loss of statistical significance.The present reanalysis does
                      not sustain the existence of an independent social
                      inequality influence on pancreatic cancer risk in Western
                      European women and men, using an index based on adult
                      education, the most relevant social indicator linked to
                      individual lifestyles, in a context of very low pancreatic
                      cancer survival from (quasi) universal public health
                      systems.The results do not support an association between
                      education and risk of pancreatic cancer.},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31160392},
      doi          = {10.1158/1055-9965.EPI-18-1153},
      url          = {https://inrepo02.dkfz.de/record/143933},
}