D200
Molekulare Grundlagen Gastrointestinaler Tumoren
Also known as:D200
| ID | I:(DE-He78)D200-20160331 |
Recent Publications
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Journal Article
Kehm, H. (First author)DKFZ* ; Zens, S. (First author)DKFZ* ; Baumann, D.DKFZ* ; Meng, Z.DKFZ* ; de Ru, A. H. ; Tjokrodirijo, R. T. N. ; Vent, C.DKFZ* ; Murawjew, O.DKFZ* ; Braun, S.DKFZ* ; Weiss, A.DKFZ* ; Bieberich, F.DKFZ* ; Konrad, A.DKFZ* ; Lucato, F.DKFZ* ; Kühner, J.DKFZ* ; Minguez, S. G.DKFZ* ; Tan, C. L.DKFZ* ; Förster, J.DKFZ* ; Salek, M.DKFZ* ; Riemer, A.DKFZ* ; Volkmar, M.DKFZ* ; van Veelen, P. ; Poschke, I. (Last author)DKFZ* ; Offringa, R. (Last author)DKFZ*
Dissection of the T cell infiltrate in mouse pancreatic tumors reveals an extensive and diverse tumor-reactive T cell repertoire.
Science advances 12(15), eadr6132 (2026) [10.1126/sciadv.adr6132]2026
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Journal Article (Review Article)
Offringa, R. (First author)DKFZ* ; Meng, Z. B.DKFZ* ; Cai, H. K. ; Shi, X. Y. ; Mei, H. ; Wu, H. S.
[Implementation of personalized T-cell therapy in the treatment of pancreatic cancer].
Zhong hua wai ke za zhi 63(8), 666-671 (2025) [DOI:10.3760/cma.j.cn112139-20250328-00164]2025
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Journal Article
Volkmar, M. (First author)DKFZ* ; Hoser, D.Extern* ; Lauenstein, C.DKFZ* ; Rebmann, J. ; Hotz-Wagenblatt, A.DKFZ* ; Rieger, J. H.DKFZ* ; Poschke, I.DKFZ* ; Becker, J.DKFZ* ; Riemer, A. B.DKFZ* ; Sprick, M.DKFZ* ; Trumpp, A.DKFZ* ; Strobel, O. ; Blankenstein, T. ; Willimsky, G.DKFZ* ; Offringa, R. (Last author)DKFZ*
Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer.
Journal for ImmunoTherapy of Cancer 13(6), e011802 (2025) [10.1136/jitc-2025-011802]2025
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Journal Article
Thiel, V. (First author)DKFZ* ; Renders, S. (First author)DKFZ* ; Panten, J. (First author)DKFZ* ; Dross, N. ; Bauer, K.DKFZ* ; Azorin, D.DKFZ* ; Henriques, V. ; Vogel, V. ; Klein, C.DKFZ* ; Leppä, A.-M.DKFZ* ; Barriuso Ortega, I.DKFZ* ; Schwickert, J.DKFZ* ; Ourailidis, I. ; Mochayedi, J. ; Mallm, J.-P.DKFZ* ; Müller-Tidow, C. ; Monyer, H.DKFZ* ; Neoptolemos, J. ; Hackert, T. ; Stegle, O.DKFZ* ; Odom, D.DKFZ* ; Offringa, R.DKFZ* ; Stenzinger, A. ; Winkler, F.DKFZ* ; Sprick, M.DKFZ* ; Trumpp, A. (Last author)DKFZ*
Characterization of single neurons reprogrammed by pancreatic cancer.
Nature 640, 1042–1051 (2025) [10.1038/s41586-025-08735-3]2025
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Journal Article
Tan, C. L. (First author)DKFZ* ; Lindner, K.DKFZ* ; Boschert, T.DKFZ* ; Meng, Z.DKFZ* ; Rodriguez Ehrenfried, A.DKFZ* ; De Roia, A.DKFZ* ; Haltenhof, G.DKFZ* ; Faenza, A. ; Imperatore, F. ; Bunse, L.DKFZ* ; Lindner, J. M. ; Harbottle, R.DKFZ* ; Ratliff, M. ; Offringa, R.DKFZ* ; Poschke, I.DKFZ* ; Platten, M. (Last author)DKFZ* ; Green, E. (Last author)DKFZ*
Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy.
Nature biotechnology 43(1), 134-142 (2025) [10.1038/s41587-024-02161-y]2025
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Preprint
Pecori, R. (First author)DKFZ* ; Casati, B. (First author)DKFZ* ; Merdler-Rabinowicz, R. ; Landesman, N. ; Sanghvi, K.DKFZ* ; Zens, S.DKFZ* ; Kipfstuhl, K.DKFZ* ; Pinamonti, V. ; Arnold, A.DKFZ* ; Lindner, J. M. ; Platten, M.DKFZ* ; Offringa, R.DKFZ* ; Carretero, R.DKFZ* ; Ruppin, E. ; Levanon, E. Y. ; Papavasiliou, F. (Last author)DKFZ*
Employing RNA editing to engineer personalized tumor-specific neoantigens (editopes)
[10.1101/2023.03.16.532918]
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Journal Article
Mowat, J. ; Carretero, R.DKFZ* ; Leder, G. ; Aiguabella Font, N. ; Neuhaus, R.DKFZ* ; Berndt, S. ; Günther, J. ; Friberg, A. ; Schäfer, M. ; Briem, H. ; Raschke, M. ; Miyatake Ondozabal, H. ; Buchmann, B. ; Boemer, U. ; Kreft, B. ; Hartung, I. V. ; Offringa, R. (Last author)DKFZ*
Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer
Journal of medicinal chemistry 67(19), 17429-17453 (2024) [10.1021/acs.jmedchem.4c01325]2024
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Journal Article
Salek, M. (First author)DKFZ* ; Förster, J. (First author)DKFZ* ; Becker, J. (First author)DKFZ* ; Meyer, M.DKFZ* ; Charoentong, P.DKFZ* ; Lyu, Y.DKFZ* ; Lindner, K.DKFZ* ; Lotsch, C.DKFZ* ; Volkmar, M. ; Momburg, F.DKFZ* ; Poschke, I.DKFZ* ; Fröhling, S.DKFZ* ; Schmitz, M.DKFZ* ; Offringa, R.DKFZ* ; Platten, M.DKFZ* ; Jäger, D.DKFZ* ; Zörnig, I.DKFZ* ; Riemer, A. (Last author)DKFZ*
optiPRM: A targeted immunopeptidomics LC-MS workflow with ultra-high sensitivity for the detection of mutation-derived tumor neoepitopes from limited input material.
Molecular & cellular proteomics 23(9), 100825 (2024) [10.1016/j.mcpro.2024.100825]2024
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Journal Article
Ehrenfried, A. R. (First author)DKFZ* ; Zens, S.DKFZ* ; Steffens, L. K.DKFZ* ; Kehm, H.DKFZ* ; Paul, A.DKFZ* ; Lauenstein, C.DKFZ* ; Volkmar, M. ; Poschke, I.DKFZ* ; Meng, Z.DKFZ* ; Offringa, R. (Last author)DKFZ*
T-Cell-Based Platform for Functional Screening of T-Cell Receptors Identified in Single-Cell RNA Sequencing Data Sets of Tumor-Infiltrating T-Cells.
Bio-protocol 14(8), e4972 (2024) [10.21769/BioProtoc.4972]2024
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Journal Article (Review Article)
Shu, J. ; Xie, W. ; Chen, Z. ; Offringa, R.DKFZ* ; Hu, Y. ; Mei, H.
The enchanting canvas of CAR technology: Unveiling its wonders in non-neoplastic diseases.
Med 5(6), 495-529 (2024) [10.1016/j.medj.2024.03.016]2024
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All known publications ...
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