Journal Article DKFZ-2019-01813

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Localization regime in diffusion NMR: Theory and experiments.

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2019
Elsevier Amsterdam [u.a.]

Journal of magnetic resonance 305, 162 - 174 () [10.1016/j.jmr.2019.06.016]
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Abstract: In this work we investigate the emergence of the localization regime for diffusion NMR in various geometries: inside slabs, inside cylinders and outside rods arranged on a square array. At high gradients, the transverse magnetization is strongly attenuated in the bulk, whereas the macroscopic signal is formed by the remaining magnetization localized near boundaries of the sample. As a consequence, the signal is particularly sensitive to the microstructure. The theoretical analysis relies on recent mathematical advances on the study of the Bloch-Torrey equation. Experiments were conducted with hyperpolarized xenon-129 gas in 3D-printed phantoms and show an excellent agreement with numerical simulations and theoretical predictions. Our mathematical arguments and experimental evidence indicate that the localization regime with a stretched-exponential decay of the macroscopic signal is a generic feature of diffusion NMR that can be observed at moderately high gradients in most NMR scanners.

Classification:

Contributing Institute(s):
  1. Medizinische Physik in der Radiologie (E020)
Research Program(s):
  1. 315 - Imaging and radiooncology (POF3-315) (POF3-315)

Appears in the scientific report 2019
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 Record created 2019-08-06, last modified 2024-02-29



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