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000144625 0247_ $$2doi$$a10.1016/j.jpsychores.2019.109746
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000144625 0247_ $$2ISSN$$a1879-1360
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000144625 037__ $$aDKFZ-2019-02067
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000144625 1001_ $$aBernard, P.$$b0
000144625 245__ $$aEffects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses.
000144625 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2019
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000144625 520__ $$aTo evaluate the effects of exercise interventions on sleep disturbances and sleep quality in patients with mixed cancer diagnoses, and identify demographic, clinical, and intervention-related moderators of these effects.Individual patient data (IPD) and aggregated meta-analyses of randomized controlled trials (RCTs). Using data from the Predicting OptimaL cAncer RehabIlitation and Supportive care project, IPD of 2173 adults (mean age = 54.8) with cancer from 17 RCTs were analyzed. A complementary systematic search was conducted (until November 2018) to study the overall effects and test the representativeness of analyzed IPD. Effect sizes of exercise effects on self-reported sleep outcomes were calculated for all included RCTs. Linear mixed-effect models were used to evaluate the effects of exercise on post-intervention outcome values, adjusting for baseline values. Moderator effects were studied by testing interactions for demographic, clinical and intervention-related characteristics.For all 27 eligible RCTs from the updated search, exercise interventions significantly decreased sleep disturbances in adults with cancer (g = -0.09, 95% CI [-0.16; -0.02]). No significant effect was obtained for sleep quality. RCTs included in IPD analyses constituted a representative sample of the published literature. The intervention effects on sleep disturbances were not significantly moderated by any demographic, clinical, or intervention-related factor, nor by sleep disturbances.This meta-analysis provides some evidence that, compared to control conditions, exercise interventions may improve sleep disturbances, but not sleep quality, in cancer patients, although this effect is of a small magnitude. Among the investigated variables, none was found to significantly moderate the effect of exercise interventions on sleep disturbances.
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000144625 7001_ $$aSavard, J.$$b1
000144625 7001_ $$0P:(DE-He78)a0c2037d9054be26907a05ae520d5756$$aSteindorf, K.$$b2$$udkfz
000144625 7001_ $$aSweegers, M. G.$$b3
000144625 7001_ $$aCourneya, K. S.$$b4
000144625 7001_ $$aNewton, R. U.$$b5
000144625 7001_ $$aAaronson, N. K.$$b6
000144625 7001_ $$aJacobsen, P. B.$$b7
000144625 7001_ $$aMay, A. M.$$b8
000144625 7001_ $$aGalvao, D. A.$$b9
000144625 7001_ $$aChinapaw, M. J.$$b10
000144625 7001_ $$aStuiver, M. M.$$b11
000144625 7001_ $$aGriffith, K. A.$$b12
000144625 7001_ $$aMesters, I.$$b13
000144625 7001_ $$aKnoop, H.$$b14
000144625 7001_ $$aGoedendorp, M. M.$$b15
000144625 7001_ $$aBohus, M.$$b16
000144625 7001_ $$aThorsen, L.$$b17
000144625 7001_ $$0P:(DE-He78)a61f4aa78cf76f21fc0e6e66e211b905$$aSchmidt, M. E.$$b18$$udkfz
000144625 7001_ $$aUlrich, C. M.$$b19
000144625 7001_ $$aSonke, G. S.$$b20
000144625 7001_ $$avan Harten, W.$$b21
000144625 7001_ $$aWinters-Stone, K. M.$$b22
000144625 7001_ $$aVelthuis, M. J.$$b23
000144625 7001_ $$aTaaffe, D. R.$$b24
000144625 7001_ $$avan Mechelen, W.$$b25
000144625 7001_ $$aKersten, M. J.$$b26
000144625 7001_ $$aNollet, F.$$b27
000144625 7001_ $$aWenzel, J.$$b28
000144625 7001_ $$aWiskemann, J.$$b29
000144625 7001_ $$aVerdonck-de Leeuw, I. M.$$b30
000144625 7001_ $$aBrug, J.$$b31
000144625 7001_ $$aBuffart, L. M.$$b32
000144625 773__ $$0PERI:(DE-600)1500642-6$$a10.1016/j.jpsychores.2019.109746$$gVol. 124, p. 109746 -$$p109746$$tJournal of psychosomatic research$$v124$$x0022-3999$$y2019
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