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@ARTICLE{Bernard:144625,
      author       = {P. Bernard and J. Savard and K. Steindorf$^*$ and M. G.
                      Sweegers and K. S. Courneya and R. U. Newton and N. K.
                      Aaronson and P. B. Jacobsen and A. M. May and D. A. Galvao
                      and M. J. Chinapaw and M. M. Stuiver and K. A. Griffith and
                      I. Mesters and H. Knoop and M. M. Goedendorp and M. Bohus
                      and L. Thorsen and M. E. Schmidt$^*$ and C. M. Ulrich and G.
                      S. Sonke and W. van Harten and K. M. Winters-Stone and M. J.
                      Velthuis and D. R. Taaffe and W. van Mechelen and M. J.
                      Kersten and F. Nollet and J. Wenzel and J. Wiskemann and I.
                      M. Verdonck-de Leeuw and J. Brug and L. M. Buffart},
      title        = {{E}ffects and moderators of exercise on sleep in adults
                      with cancer: {I}ndividual patient data and aggregated
                      meta-analyses.},
      journal      = {Journal of psychosomatic research},
      volume       = {124},
      issn         = {0022-3999},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DKFZ-2019-02067},
      pages        = {109746},
      year         = {2019},
      abstract     = {To evaluate the effects of exercise interventions on sleep
                      disturbances and sleep quality in patients with mixed cancer
                      diagnoses, and identify demographic, clinical, and
                      intervention-related moderators of these effects.Individual
                      patient data (IPD) and aggregated meta-analyses of
                      randomized controlled trials (RCTs). Using data from the
                      Predicting OptimaL cAncer RehabIlitation and Supportive care
                      project, IPD of 2173 adults (mean age = 54.8) with
                      cancer from 17 RCTs were analyzed. A complementary
                      systematic search was conducted (until November 2018) to
                      study the overall effects and test the representativeness of
                      analyzed IPD. Effect sizes of exercise effects on
                      self-reported sleep outcomes were calculated for all
                      included RCTs. Linear mixed-effect models were used to
                      evaluate the effects of exercise on post-intervention
                      outcome values, adjusting for baseline values. Moderator
                      effects were studied by testing interactions for
                      demographic, clinical and intervention-related
                      characteristics.For all 27 eligible RCTs from the updated
                      search, exercise interventions significantly decreased sleep
                      disturbances in adults with cancer (g = -0.09, $95\%$ CI
                      [-0.16; -0.02]). No significant effect was obtained for
                      sleep quality. RCTs included in IPD analyses constituted a
                      representative sample of the published literature. The
                      intervention effects on sleep disturbances were not
                      significantly moderated by any demographic, clinical, or
                      intervention-related factor, nor by sleep disturbances.This
                      meta-analysis provides some evidence that, compared to
                      control conditions, exercise interventions may improve sleep
                      disturbances, but not sleep quality, in cancer patients,
                      although this effect is of a small magnitude. Among the
                      investigated variables, none was found to significantly
                      moderate the effect of exercise interventions on sleep
                      disturbances.},
      subtyp        = {Review Article},
      cin          = {C110},
      ddc          = {610},
      cid          = {I:(DE-He78)C110-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31443811},
      doi          = {10.1016/j.jpsychores.2019.109746},
      url          = {https://inrepo02.dkfz.de/record/144625},
}