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024 7 _ |a 10.1016/j.jpsychores.2019.109746
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024 7 _ |a 1879-1360
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037 _ _ |a DKFZ-2019-02067
041 _ _ |a eng
082 _ _ |a 610
100 1 _ |a Bernard, P.
|b 0
245 _ _ |a Effects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses.
260 _ _ |a Amsterdam [u.a.]
|c 2019
|b Elsevier Science
336 7 _ |a article
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520 _ _ |a To evaluate the effects of exercise interventions on sleep disturbances and sleep quality in patients with mixed cancer diagnoses, and identify demographic, clinical, and intervention-related moderators of these effects.Individual patient data (IPD) and aggregated meta-analyses of randomized controlled trials (RCTs). Using data from the Predicting OptimaL cAncer RehabIlitation and Supportive care project, IPD of 2173 adults (mean age = 54.8) with cancer from 17 RCTs were analyzed. A complementary systematic search was conducted (until November 2018) to study the overall effects and test the representativeness of analyzed IPD. Effect sizes of exercise effects on self-reported sleep outcomes were calculated for all included RCTs. Linear mixed-effect models were used to evaluate the effects of exercise on post-intervention outcome values, adjusting for baseline values. Moderator effects were studied by testing interactions for demographic, clinical and intervention-related characteristics.For all 27 eligible RCTs from the updated search, exercise interventions significantly decreased sleep disturbances in adults with cancer (g = -0.09, 95% CI [-0.16; -0.02]). No significant effect was obtained for sleep quality. RCTs included in IPD analyses constituted a representative sample of the published literature. The intervention effects on sleep disturbances were not significantly moderated by any demographic, clinical, or intervention-related factor, nor by sleep disturbances.This meta-analysis provides some evidence that, compared to control conditions, exercise interventions may improve sleep disturbances, but not sleep quality, in cancer patients, although this effect is of a small magnitude. Among the investigated variables, none was found to significantly moderate the effect of exercise interventions on sleep disturbances.
536 _ _ |a 313 - Cancer risk factors and prevention (POF3-313)
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700 1 _ |a Savard, J.
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700 1 _ |a Steindorf, K.
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700 1 _ |a Sweegers, M. G.
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700 1 _ |a Courneya, K. S.
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700 1 _ |a Newton, R. U.
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700 1 _ |a Aaronson, N. K.
|b 6
700 1 _ |a Jacobsen, P. B.
|b 7
700 1 _ |a May, A. M.
|b 8
700 1 _ |a Galvao, D. A.
|b 9
700 1 _ |a Chinapaw, M. J.
|b 10
700 1 _ |a Stuiver, M. M.
|b 11
700 1 _ |a Griffith, K. A.
|b 12
700 1 _ |a Mesters, I.
|b 13
700 1 _ |a Knoop, H.
|b 14
700 1 _ |a Goedendorp, M. M.
|b 15
700 1 _ |a Bohus, M.
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700 1 _ |a Thorsen, L.
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700 1 _ |a Schmidt, M. E.
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700 1 _ |a Ulrich, C. M.
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700 1 _ |a Sonke, G. S.
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700 1 _ |a van Harten, W.
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700 1 _ |a Winters-Stone, K. M.
|b 22
700 1 _ |a Velthuis, M. J.
|b 23
700 1 _ |a Taaffe, D. R.
|b 24
700 1 _ |a van Mechelen, W.
|b 25
700 1 _ |a Kersten, M. J.
|b 26
700 1 _ |a Nollet, F.
|b 27
700 1 _ |a Wenzel, J.
|b 28
700 1 _ |a Wiskemann, J.
|b 29
700 1 _ |a Verdonck-de Leeuw, I. M.
|b 30
700 1 _ |a Brug, J.
|b 31
700 1 _ |a Buffart, L. M.
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773 _ _ |a 10.1016/j.jpsychores.2019.109746
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