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@ARTICLE{ObnSantacana:148331,
author = {M. Obón-Santacana and L. Luján-Barroso and H. Freisling
and S. Naudin and M.-C. Boutron-Ruault and F. R. Mancini and
V. Rebours and T. Kühn$^*$ and V. Katzke$^*$ and H. Boeing
and A. Tjønneland and A. Olsen and K. Overvad and C.
Lasheras and M. Rodríguez-Barranco and P. Amiano and C.
Santiuste and E. Ardanaz and K.-T. Khaw and N. J. Wareham
and J. A. Schmidt and D. Aune and A. Trichopoulou and P.
Thriskos and E. Peppa and G. Masala and S. Grioni and R.
Tumino and S. Panico and B. Bueno-de-Mesquita and V.
Sciannameo and R. Vermeulen and E. Sonestedt and M. Sund and
E. Weiderpass and G. Skeie and C. A. González and E. Riboli
and E. J. Duell},
title = {{C}onsumption of nuts and seeds and pancreatic ductal
adenocarcinoma risk in the {E}uropean {P}rospective
{I}nvestigation into {C}ancer and {N}utrition.},
journal = {International journal of cancer},
volume = {146},
number = {1},
issn = {1097-0215},
address = {Bognor Regis},
publisher = {Wiley-Liss},
reportid = {DKFZ-2019-02887},
pages = {76 - 84},
year = {2020},
abstract = {Four epidemiologic studies have assessed the association
between nut intake and pancreatic cancer risk with
contradictory results. The present study aims to investigate
the relation between nut intake (including seeds) and
pancreatic ductal adenocarcinoma (PDAC) risk in the European
Prospective Investigation into Cancer and Nutrition (EPIC)
study. Cox proportional hazards models were used to estimate
hazards ratio (HR) and $95\%$ confidence intervals $(95\%$
CI) for nut intake and PDAC risk. Information on intake of
nuts was obtained from the EPIC country-specific dietary
questionnaires. After a mean follow-up of 14 years,
476,160 participants were eligible for the present study and
included 1,283 PDAC cases. No association was observed
between consumption of nuts and PDAC risk (highest intake vs
nonconsumers: HR, 0.89; $95\%$ CI, 0.72-1.10;
p-trend = 0.70). Furthermore, no evidence for
effect-measure modification was observed when different
subgroups were analyzed. Overall, in EPIC, the highest
intake of nuts was not statistically significantly
associated with PDAC risk.},
cin = {C020},
ddc = {610},
cid = {I:(DE-He78)C020-20160331},
pnm = {313 - Cancer risk factors and prevention (POF3-313)},
pid = {G:(DE-HGF)POF3-313},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:31107546},
doi = {10.1002/ijc.32415},
url = {https://inrepo02.dkfz.de/record/148331},
}