Journal Article

DKFZ-2019-02887

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition.

Obón-Santacana, M. ; Luján-Barroso, L. ; Freisling, H. ; Naudin, S. ; Boutron-Ruault, M.-C. ; Mancini, F. R. ; Rebours, V. ; Kühn, T.DKFZ* ; Katzke, V.DKFZ* ; Boeing, H. ; Tjønneland, A. ; Olsen, A. ; Overvad, K. ; Lasheras, C. ; Rodríguez-Barranco, M. ; Amiano, P. ; Santiuste, C. ; Ardanaz, E. ; Khaw, K.-T. ; Wareham, N. J. ; Schmidt, J. A. ; Aune, D. ; Trichopoulou, A. ; Thriskos, P. ; Peppa, E. ; Masala, G. ; Grioni, S. ; Tumino, R. ; Panico, S. ; Bueno-de-Mesquita, B. ; Sciannameo, V. ; Vermeulen, R. ; Sonestedt, E. ; Sund, M. ; Weiderpass, E. ; Skeie, G. ; González, C. A. ; Riboli, E. ; Duell, E. J.

2020
Wiley-Liss Bognor Regis

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Please use a persistent id in citations: doi:10.1002/ijc.32415

Abstract: Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estimate hazards ratio (HR) and 95% confidence intervals (95% CI) for nut intake and PDAC risk. Information on intake of nuts was obtained from the EPIC country-specific dietary questionnaires. After a mean follow-up of 14 years, 476,160 participants were eligible for the present study and included 1,283 PDAC cases. No association was observed between consumption of nuts and PDAC risk (highest intake vs nonconsumers: HR, 0.89; 95% CI, 0.72-1.10; p-trend = 0.70). Furthermore, no evidence for effect-measure modification was observed when different subgroups were analyzed. Overall, in EPIC, the highest intake of nuts was not statistically significantly associated with PDAC risk.

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Contributing Institute(s):

1. Epidemiologie von Krebserkrankungen (C020)

Research Program(s):

1. 313 - Cancer risk factors and prevention (POF3-313) (POF3-313)

Appears in the scientific report 2020

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Database coverage:
; BIOSIS Previews ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; IF >= 5 ; JCR ; NCBI Molecular Biology Database ; Nationallizenz ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Web of Science Core Collection

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