Journal Article (Editorial)

DKFZ-2019-02969

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Probing Medulloblastoma Initiation at the Single-Cell Level.

Okonechnikov, K. (First author)DKFZ* ; Pfister, S. M.DKFZ* ; Kutscher, L. (Last author)DKFZ*

2019
Elsevier Amsterdam

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Please use a persistent id in citations: doi:10.1016/j.trecan.2019.10.002

Abstract: Medulloblastoma is a pediatric brain tumor arising from the developing cerebellum. Despite significant strides in classifying tumor subgroups and identifying underlying genetic mutations, progress in clinical outcomes has been notably slower. About 30% of patients experience relapse after treatment, possibly because of our inability to identify and eliminate the cancer stem cells. Zhang et al. recently investigated these cells in the SHH subgroup of medulloblastoma and identified drugs that may target them.

Note: EA:B062LA:B062Editorial MaterialSpotlight

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Contributing Institute(s):

1. Pädiatrische Neuroonkologie (B062)
2. DKTK Heidelberg (L101)

Research Program(s):

1. 312 - Functional and structural genomics (POF3-312) (POF3-312)

Appears in the scientific report 2019

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Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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