TY  - JOUR
AU  - Erhardt, Sylvia
AU  - Stoecklin, Georg
TI  - The heat's on: nuclear stress bodies signal intron retention.
JO  - The EMBO journal
VL  - 39
IS  - 3
SN  - 1460-2075
CY  - Hoboken, NJ [u.a.]
PB  - Wiley
M1  - DKFZ-2020-00162
SP  - e104154
PY  - 2020
N1  - DKFZ-ZMBH Alliance2020 Feb 3;39(3):e104154
AB  - The cellular response to heat shock requires massive adaptation of gene expression driven by the transcription factor HSF1, which assembles in nuclear stress bodies together with human satellite III RNA and numerous splicing factors. In this issue of The EMBO Journal, Ninomiya et al demonstrate that nuclear stress bodies serve as a platform for phosphorylation of the SR protein SRSF9 by the CLK1 kinase, which promotes retention of a large number of introns during the recovery phase from heat shock.
LB  - PUB:(DE-HGF)16
C6  - pmid:31919860
DO  - DOI:10.15252/embj.2019104154
UR  - https://inrepo02.dkfz.de/record/153080
ER  -