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@ARTICLE{Pedersen:153184,
      author       = {M. S. Pedersen and M. Müller and T. Rülicke and N.
                      Leitner and R. Kain and H. Regele and S. Wang$^*$ and H.-J.
                      Gröne$^*$ and S. Rong and H. Haller and F. Gueler and A. J.
                      Rees and D. Kerjaschki},
      title        = {{L}ymphangiogenesis in a mouse model of renal transplant
                      rejection extends life span of the recipients.},
      journal      = {Kidney international},
      volume       = {97},
      number       = {1},
      issn         = {0085-2538},
      address      = {New York, NY},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2020-00237},
      pages        = {89 - 94},
      year         = {2020},
      abstract     = {Renal allograft rejection can be prevented by immunological
                      tolerance, which may be associated with de novo formed
                      lymphatic vessels in the donor kidney after transplantation
                      in man. A suitable mouse model of renal allograft rejection
                      in which lymphangiogenesis can be deliberately induced in
                      the graft is critical for elucidating the mechanisms
                      responsible for the association between attenuated
                      transplant rejection and abundance of lymphatic vessels.
                      Here we describe the development of a novel mouse model of
                      rapid renal transplant rejection in which transgenic
                      induction of lymphangiogenesis in the immune-incompatible
                      graft greatly extends its survival time. Thus, our novel
                      approach may facilitate exploitation of lymphangiogenesis in
                      the grafted organ.},
      cin          = {G130},
      ddc          = {610},
      cid          = {I:(DE-He78)G130-20160331},
      pnm          = {319H - Addenda (POF3-319H)},
      pid          = {G:(DE-HGF)POF3-319H},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:31718844},
      doi          = {10.1016/j.kint.2019.07.027},
      url          = {https://inrepo02.dkfz.de/record/153184},
}