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000153719 1001_ $$aPacker, Roger J$$b0
000153719 245__ $$aImplications of New Understandings of Gliomas in Children and Adults with NF1: Report of a Consensus Conference.
000153719 260__ $$aOxford$$bOxford Univ. Press$$c2020
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000153719 500__ $$a2020 Jun 9;22(6):773-784
000153719 520__ $$aGliomas are the most common primary central nervous system tumors occurring in children and adults with neurofibromatosis type I (NF1). Over the past decade, discoveries of the molecular basis of low-grade gliomas (LGGs) have led to new approaches for diagnosis and treatments. However, these new understandings have not been fully applied to the management of NF1-associated gliomas. A consensus panel consisting of experts in NF1 and gliomas was convened to review the current molecular knowledge of NF1-associated low grade 'transformed' and high-grade gliomas; insights gained from mouse models of NF1-LGGs; challenges in diagnosing and treating older patients with NF1-associated gliomas; and advances in molecular targeted treatment and potential immunologic treatment of these tumors. Next steps are recommended to advance the management and outcomes for NF1-associated gliomas.
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000153719 7001_ $$aBlakeley, Jaishri O$$b3
000153719 7001_ $$aBouffet, Eric$$b4
000153719 7001_ $$aFisher, Michael J$$b5
000153719 7001_ $$aHwang, Eugene$$b6
000153719 7001_ $$aHawkins, Cynthia$$b7
000153719 7001_ $$aKilburn, Lindsay$$b8
000153719 7001_ $$aMacDonald, Tobey$$b9
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000153719 7001_ $$aRood, Brian$$b11
000153719 7001_ $$aRodriguez, Fausto J$$b12
000153719 7001_ $$aTabori, Uri$$b13
000153719 7001_ $$aRamaswamy, Vijay$$b14
000153719 7001_ $$aZhu, Yuan$$b15
000153719 7001_ $$aFangusaro, Jason$$b16
000153719 7001_ $$aJohnston, Stephen A$$b17
000153719 7001_ $$aGutmann, David H$$b18
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