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@ARTICLE{Packer:153719,
      author       = {R. J. Packer and A. Iavarone and D. T. W. Jones$^*$ and J.
                      O. Blakeley and E. Bouffet and M. J. Fisher and E. Hwang and
                      C. Hawkins and L. Kilburn and T. MacDonald and S. M.
                      Pfister$^*$ and B. Rood and F. J. Rodriguez and U. Tabori
                      and V. Ramaswamy and Y. Zhu and J. Fangusaro and S. A.
                      Johnston and D. H. Gutmann},
      title        = {{I}mplications of {N}ew {U}nderstandings of {G}liomas in
                      {C}hildren and {A}dults with {NF}1: {R}eport of a
                      {C}onsensus {C}onference.},
      journal      = {Neuro-Oncology},
      volume       = {22},
      number       = {6},
      issn         = {1523-5866},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {DKFZ-2020-00416},
      pages        = {773-784},
      year         = {2020},
      note         = {2020 Jun 9;22(6):773-784},
      abstract     = {Gliomas are the most common primary central nervous system
                      tumors occurring in children and adults with
                      neurofibromatosis type I (NF1). Over the past decade,
                      discoveries of the molecular basis of low-grade gliomas
                      (LGGs) have led to new approaches for diagnosis and
                      treatments. However, these new understandings have not been
                      fully applied to the management of NF1-associated gliomas. A
                      consensus panel consisting of experts in NF1 and gliomas was
                      convened to review the current molecular knowledge of
                      NF1-associated low grade 'transformed' and high-grade
                      gliomas; insights gained from mouse models of NF1-LGGs;
                      challenges in diagnosing and treating older patients with
                      NF1-associated gliomas; and advances in molecular targeted
                      treatment and potential immunologic treatment of these
                      tumors. Next steps are recommended to advance the management
                      and outcomes for NF1-associated gliomas.},
      cin          = {B360 / B062},
      ddc          = {610},
      cid          = {I:(DE-He78)B360-20160331 / I:(DE-He78)B062-20160331},
      pnm          = {312 - Functional and structural genomics (POF3-312)},
      pid          = {G:(DE-HGF)POF3-312},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32055852},
      doi          = {10.1093/neuonc/noaa036},
      url          = {https://inrepo02.dkfz.de/record/153719},
}