000165936 001__ 165936
000165936 005__ 20240229133154.0
000165936 0247_ $$2doi$$a10.1038/s41597-020-00716-7
000165936 0247_ $$2pmid$$apmid:33188205
000165936 0247_ $$2ISSN$$a2052-4436
000165936 0247_ $$2ISSN$$a2052-4463
000165936 0247_ $$2altmetric$$aaltmetric:94208088
000165936 037__ $$aDKFZ-2020-02487
000165936 041__ $$aeng
000165936 082__ $$a500
000165936 1001_ $$00000-0003-2598-8388$$aCai, Lina$$b0
000165936 245__ $$aGenome-wide association analysis of type 2 diabetes in the EPIC-InterAct study.
000165936 260__ $$aLondon$$bNature Publ. Group$$c2020
000165936 3367_ $$2DRIVER$$aarticle
000165936 3367_ $$2DataCite$$aOutput Types/Journal article
000165936 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1611752104_17269
000165936 3367_ $$2BibTeX$$aARTICLE
000165936 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000165936 3367_ $$00$$2EndNote$$aJournal Article
000165936 500__ $$a2020 Nov 13;7(1):393
000165936 520__ $$aType 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our understanding of its biological mechanisms and translational insights is still limited. The EPIC-InterAct project, centred in 8 countries in the European Prospective Investigations into Cancer and Nutrition study, is one of the largest prospective studies of T2D. Established as a nested case-cohort study to investigate the interplay between genetic and lifestyle behavioural factors on the risk of T2D, a total of 12,403 individuals were identified as incident T2D cases, and a representative sub-cohort of 16,154 individuals was selected from a larger cohort of 340,234 participants with a follow-up time of 3.99 million person-years. We describe the results from a genome-wide association analysis between more than 8.9 million SNPs and T2D risk among 22,326 individuals (9,978 cases and 12,348 non-cases) from the EPIC-InterAct study. The summary statistics to be shared provide a valuable resource to facilitate further investigations into the genetics of T2D.
000165936 536__ $$0G:(DE-HGF)POF3-323$$a323 - Metabolic Dysfunction as Risk Factor (POF3-323)$$cPOF3-323$$fPOF III$$x0
000165936 588__ $$aDataset connected to CrossRef, PubMed,
000165936 7001_ $$00000-0002-8616-6444$$aWheeler, Eleanor$$b1
000165936 7001_ $$aKerrison, Nicola D$$b2
000165936 7001_ $$00000-0003-3137-6337$$aLuan, Jian'an$$b3
000165936 7001_ $$00000-0001-9251-070X$$aDeloukas, Panos$$b4
000165936 7001_ $$aFranks, Paul W$$b5
000165936 7001_ $$aAmiano, Pilar$$b6
000165936 7001_ $$aArdanaz, Eva$$b7
000165936 7001_ $$aBonet, Catalina$$b8
000165936 7001_ $$aFagherazzi, Guy$$b9
000165936 7001_ $$00000-0002-0187-3263$$aGroop, Leif C$$b10
000165936 7001_ $$0P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aKaaks, Rudolf$$b11$$udkfz
000165936 7001_ $$00000-0002-9637-3869$$aHuerta, José María$$b12
000165936 7001_ $$00000-0002-5758-9069$$aMasala, Giovanna$$b13
000165936 7001_ $$00000-0002-5652-8459$$aNilsson, Peter M$$b14
000165936 7001_ $$00000-0001-6429-7921$$aOvervad, Kim$$b15
000165936 7001_ $$aPala, Valeria$$b16
000165936 7001_ $$aPanico, Salvatore$$b17
000165936 7001_ $$aRodriguez-Barranco, Miguel$$b18
000165936 7001_ $$aRolandsson, Olov$$b19
000165936 7001_ $$aSacerdote, Carlotta$$b20
000165936 7001_ $$00000-0002-0830-5277$$aSchulze, Matthias B$$b21
000165936 7001_ $$aSpijkerman, Annemieke M W$$b22
000165936 7001_ $$aTjonneland, Anne$$b23
000165936 7001_ $$00000-0003-2666-414X$$aTumino, Rosario$$b24
000165936 7001_ $$00000-0002-4605-435X$$avan der Schouw, Yvonne T$$b25
000165936 7001_ $$aSharp, Stephen J$$b26
000165936 7001_ $$00000-0002-5041-248X$$aForouhi, Nita G$$b27
000165936 7001_ $$aRiboli, Elio$$b28
000165936 7001_ $$aMcCarthy, Mark I$$b29
000165936 7001_ $$00000-0001-5800-4520$$aBarroso, Inês$$b30
000165936 7001_ $$00000-0002-5017-7344$$aLangenberg, Claudia$$b31
000165936 7001_ $$aWareham, Nicholas J$$b32
000165936 773__ $$0PERI:(DE-600)2775191-0$$a10.1038/s41597-020-00716-7$$gVol. 7, no. 1, p. 393$$n1$$p393$$tScientific data$$v7$$x2052-4463$$y2020
000165936 909CO $$ooai:inrepo02.dkfz.de:165936$$pVDB
000165936 9101_ $$0I:(DE-588b)2036810-0$$6P:(DE-He78)4b2dc91c9d1ac33a1c0e0777d0c1697a$$aDeutsches Krebsforschungszentrum$$b11$$kDKFZ
000165936 9131_ $$0G:(DE-HGF)POF3-323$$1G:(DE-HGF)POF3-320$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lHerz-Kreislauf-Stoffwechselerkrankungen$$vMetabolic Dysfunction as Risk Factor$$x0
000165936 9141_ $$y2020
000165936 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bSCI DATA : 2018$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Blind peer review$$d2020-09-06
000165936 915__ $$0LIC:(DE-HGF)CCBYNV$$2V:(DE-HGF)$$aCreative Commons Attribution CC BY (No Version)$$bDOAJ$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bSCI DATA : 2018$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2020-09-06
000165936 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2020-09-06
000165936 9201_ $$0I:(DE-He78)C020-20160331$$kC020$$lC020 Epidemiologie von Krebs$$x0
000165936 980__ $$ajournal
000165936 980__ $$aVDB
000165936 980__ $$aI:(DE-He78)C020-20160331
000165936 980__ $$aUNRESTRICTED