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@MASTERSTHESIS{Hehn:166148,
      author       = {L. Hehn$^*$},
      title        = {{D}evelopment of a {N}ovel {M}ethod for {M}easuring
                      the{O}xygen {C}onsumption {R}ate of {C}ancer {C}ells in
                      {V}itrousing {Q}uenched {L}uminescence {O}xygen {S}ensors},
      school       = {Universität Heidelberg},
      type         = {Masterarbeit},
      reportid     = {DKFZ-2020-02656},
      year         = {2020},
      note         = {Masterarbeit, Universität Heidelberg, 2020},
      abstract     = {The increase of cellular radiosensitivity due to the
                      presence of oxygen has been widelyestablished [1]–[3].
                      Comparatively little is known about the effect of cellular
                      oxygenconsumption on the results of radiotherapy, however.In
                      this project, a novel method for measuring cellular oxygen
                      consumption in vitro wasdeveloped and used to measure the
                      oxygen consumption rate of eight cancer cell lines.The rates
                      were compared with data from clonogenic assays of these cell
                      lines to investigateto which extent the oxygen consumption
                      rate can make predictions of cellularradiosensitivity.Oxygen
                      sensing was done using non-invasive sensors based on the
                      principle of quenchedluminescence, which allow accurate,
                      real-time measurements that do not disturb thesample.},
      cin          = {E041},
      cid          = {I:(DE-He78)E041-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)19},
      url          = {https://inrepo02.dkfz.de/record/166148},
}