312
Functional and Structural Genomics
Funktionelle und strukturelle Genomforschung
Grant period | 2021 - 2026 |
Funding body | Helmholtz Gemeinschaft Deutscher Forschungszentren |
Categories | Leistungskategorie I ; Topic |
Identifier | G:(DE-HGF)POF4-312 |
⇧ Krebsforschung ⇧
Recent Publications
All known publications ...
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Journal Article (Review Article)
Karreman, M. A. (First author)DKFZ* ; Winkler, F. (Last author)DKFZ*
Cancer neuroscience of brain metastasis: When in Rome, do as the Romans do.
Neuron 113(17), 2740 - 2759 (2025) [10.1016/j.neuron.2025.08.003]2025
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Groff, K. J. ; Patel, R. V. ; Feng, Y. ; Ghosh, H. S. ; Millares Chavez, M. A. ; O'Brien, J. ; Chen, W. C. ; Nitturi, V. ; Save, A. V. ; Youngblood, M. W. ; Horbinski, C. M. ; Chandler, J. P. ; Ehret, F.DKFZ* ; Gui, C. ; Wang, J. Z. ; Park, K. ; Ajmera, S. ; Rosenblum, M. ; Suwala, A. K.DKFZ* ; Kresbach, C. ; Mount, C. W. ; Schüller, U. ; Santagata, S. ; Sahm, F.DKFZ* ; Bale, T. A. ; Jackson, C. ; Richardson, T. E. ; Cai, C. ; Nassiri, F. ; Zadeh, G. ; Kaul, D. ; Capper, D.DKFZ* ; Magill, S. T. ; Golfinos, J. G. ; Sen, C. ; Patel, A. J. ; Raleigh, D. R. ; Moliterno, J. ; Pacione, D. ; Snuderl, M. ; Bi, W. L.
The effect of TERT promoter mutation on predicting meningioma outcomes: a multi-institutional cohort analysis.
The lancet / Oncology 26(9), 1178 - 1190 (2025) [10.1016/S1470-2045(25)00422-X]2025
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Umbaugh, C. S. (First author)DKFZ* ; Groth, M. (First author)DKFZ* ; Erkut, C.DKFZ* ; Lee, K.DKFZ* ; Marinho, J. ; Linder, S.DKFZ* ; Iser, F.DKFZ* ; Kapp, J.DKFZ* ; Schroeter, P.DKFZ* ; Dolaner, S.DKFZ* ; Kayserili, A.DKFZ* ; Helm, D.DKFZ* ; Schneider, M.DKFZ* ; Hartmann, J.DKFZ* ; Walch, P.DKFZ* ; Barth, T. F. E. ; Mellert, K. ; Dreier, B. ; Schaefer, J. V. ; Plückthun, A. ; Fröhling, S. (Last author)DKFZ* ; Scholl, C. (Last author)DKFZ*
Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma.
Science advances 11(36), eadu2796 (2025) [10.1126/sciadv.adu2796]2025
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Journal Article (Review Article)
Wasserman, J. D. ; Schneider, K. W. ; Achatz, M.-I. ; Nakano, Y. ; Zelley, K. ; Gallinger, B. ; Bauer, A. J. ; Becktell, K. D. ; Wassner, A. J. ; Raiti, L. ; Doria, A. S. ; States, L. J. ; Stratakis, C. A. ; Brodeur, G. M. ; Diller, L. R. ; Kamihara, J. ; Malkin, D. ; Pajtler, K.DKFZ* ; Tamura, C. ; Villani, A. ; Widjaja, E. ; Das, A. ; Rednam, S. P.
Updated Recommendations for Pediatric Surveillance in Hereditary Endocrine Neoplasia Syndromes: Multiple Endocrine Neoplasias, Hyperparathyroidism-Jaw Tumor Syndrome, and Carney Complex.
Clinical cancer research 31(17), 3628 - 3637 (2025) [10.1158/1078-0432.CCR-24-3860]2025
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Journal Article (Review Article)
Lujumba, I. ; Adam, Y. ; Ziaei Jam, H. ; Isewon, I. ; Monnakgotla, N. ; Li, Y. ; Onyido, B. ; Fredrick, K. ; Adegoke, F. ; Emmanuel, J. ; Adeyemi, J. ; Ibitoye, O. ; Owusu-Ansah, S. ; Akanle, M. B. ; Joseph, H. ; Nsubuga, M. ; Galiwango, R. ; Okitwi, M. ; Magdalene, N. ; Walter, O. ; Mngadi, Z. ; Adebiyi, M. ; Oyelade, J. ; Nel, M. ; Jjingo, D. ; Gymrek, M. ; Adebiyi, E. F. (Last author)DKFZ*
A practical guide to identifying associations between tandem repeats and complex human traits using consensus genotypes from multiple tools.
Nature protocols nn, nn (2025) [10.1038/s41596-025-01231-y]2025
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Journal Article
Lindenhofer, D. ; Bauman, J. R. ; Hawkins, J. A.DKFZ* ; Fitzgerald, D. ; Yildiz, U. ; Jung, H. ; Korosteleva, A. ; Marttinen, M. ; Kueblbeck, M. ; Zaugg, J. B. ; Noh, K.-M. ; Dietrich, S. ; Huber, W. ; Stegle, O.DKFZ* ; Steinmetz, L. M.
Functional phenotyping of genomic variants using joint multiomic single-cell DNA-RNA sequencing.
Nature methods nn, nn (2025) [10.1038/s41592-025-02805-0]2025
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Journal Article
Wesseling, P. ; Capper, D.DKFZ* ; Reifenberger, G. ; Sarkar, C. ; Hawkins, C. ; Perry, A. ; Kleinschmidt-DeMasters, B. ; Komori, T. ; Paulus, W. ; Santosh, V. ; van den Bent, M. ; Weller, M. ; Pfister, S.DKFZ* ; Tabori, U. ; Figarella-Branger, D. ; Orr, B. A. ; Louis, D. N.
cIMPACT-NOW update 11: Proposal on adaptation of diagnostic criteria for IDH- and H3-wildtype diffuse high-grade gliomas and for posterior fossa ependymal tumors.
Brain pathology nn, nn (2025) [10.1111/bpa.70035]2025
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Kowar, A. (First author)DKFZ* ; Becker, J. (First author)DKFZ* ; Del Pizzo, R.DKFZ* ; Tang, Z.DKFZ* ; Champagne, J. ; Wellach, K.DKFZ* ; Samimi, K.DKFZ* ; Galindo-Albarrán, A. ; Körner, P.-R. ; Montenegro Navarro, J. ; Elía, A.DKFZ* ; Tilghman, F.DKFZ* ; Sakeer, H.DKFZ* ; Mendoza-Parra, M. A. ; Riemer, A.DKFZ* ; Agami, R. ; Loayza-Puch, F. (Last author)DKFZ*
Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells
Nature Communications 16(1), 8008 (2025) [10.1038/s41467-025-63405-2]2025
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McLoughlin, M. A. ; Cheloor Kovilakam, S. ; Dunn, W. G. ; Gu, M. ; Tobin, J. ; Pershad, Y. ; Williams, N. ; Leongamornlert, D. ; Dawson, K. ; Bond, L. ; Marando, L. ; Wen, S. ; Wilson, R. ; Valenzano, G. ; Symeonidou, V. ; Rak, J. ; Damaskou, A. ; Gozdecka, M. ; Liu, X. ; Barcena, C. ; Nomdedeu, J. ; Costeas, P. ; Dimitriou, I. D. ; Fiorillo, E. ; Orrù, V. ; de Almeida, J. G. ; McKerrell, T. ; Cullen, M. ; Mohorianu, I. ; Foukaneli, T. ; Warren, A. J. ; Wong, C. ; Follows, G. ; Godfrey, A. L. ; Gudgin, E. ; Cucca, F. ; McKinney, E. ; Baxter, E. J. ; Gerstung, M.DKFZ* ; Mitchell, J. ; Wiseman, D. ; Bick, A. G. ; Fabre, M. ; Quiros, P. M. ; Nangalia, J. ; Kar, S. ; Vassiliou, G. S.
Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis.
Nature genetics nn, nn (2025) [10.1038/s41588-025-02296-x]2025
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Journal Article
Herter, S. (First author)DKFZ* ; Emperador, M.DKFZ* ; Smyrilli, K.DKFZ* ; Kocher, D.DKFZ* ; Celikyürekli, S.DKFZ* ; Zeiser, C.DKFZ* ; Gerloff, X.DKFZ* ; Kreth, S.DKFZ* ; Henrich, K.-O.DKFZ* ; Maaß, K. K.DKFZ* ; Rettenmeier, J.DKFZ* ; Grünewald, T.DKFZ* ; Peterziel, H.DKFZ* ; Westermann, F.DKFZ* ; Hamacher-Brady, A. ; Witt, O.DKFZ* ; Oehme, I. (Last author)DKFZ*
High content-imaging drug synergy screening identifies specific senescence-related vulnerabilities of mesenchymal neuroblastomas.
Cell death & disease 16(1), 644 (2025) [10.1038/s41419-025-07933-1]2025
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