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Functional and Structural Genomics
Funktionelle und strukturelle Genomforschung
| Grant period | 2021 - 2026 |
| Funding body | Helmholtz Gemeinschaft Deutscher Forschungszentren |
| Categories | Leistungskategorie I ; Topic |
| Identifier | G:(DE-HGF)POF4-312 |
⇧ Krebsforschung ⇧
Recent Publications
All known publications ...
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Journal Article
Heinz, A. T. ; Schönstein, A. ; Koscielniak, E. ; Ebinger, M. ; Fuchs, J. ; Harrabi, S. ; Vokuhl, C. ; Imle, R.DKFZ* ; Stegmaier, S. ; Brecht, I. B. ; Ljungman, G. ; Juntti, H. ; Ladenstein, R. ; Kazanowska, B. ; Klingebiel, T. ; Pajtler, K. (Last author)DKFZ* ; Sparber-Sauer, M.
Children and Adolescents With Localised Non-Rhabdomyosarcoma Soft Tissue Sarcoma: Results of the CWS-96 and CWS-2002P Prospective Trials With Reclassification of the Trial Data Incorporating the Recent Soft Tissue Sarcoma Registry.
Pediatric blood & cancer nn, nn (2025) [10.1002/pbc.32159]2025
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Zeilfelder, A. (First author)DKFZ* ; Vanlier, J. ; Mölders, C.DKFZ* ; Kastl, P.DKFZ* ; Helm, B.DKFZ* ; Burbano de Lara, S.DKFZ* ; Möcklinghoff, T.DKFZ* ; Leonidou, N.DKFZ* ; Holstein, E.DKFZ* ; Vlasov, A.DKFZ* ; Held, A.DKFZ* ; Wilken, S.DKFZ* ; Hoffmann, K. ; Schicht, G. ; Scheffschick, A. ; Katerinopoulou, M. ; Giehl-Brown, E. ; Kahlert, C. ; Michalski, C. ; Seehofer, D. ; Damm, G. ; Muckenthaler, M. U. ; Schilling, M.DKFZ* ; Timmer, J. ; Klingmüller, U. (Last author)DKFZ*
Diclofenac and acetaminophen dim the acute-phase response but amplify expression of the iron regulator hepcidin in liver cancer cells.
Cell systems 16(11), 101431 (2025) [10.1016/j.cels.2025.101431]2025
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Bekavac, M. (First author)DKFZ* ; Coimbra, R. (First author)DKFZ* ; Busa, V. (First author)DKFZ* ; Behm, M.DKFZ* ; Wagner, R.DKFZ* ; Goncalves, A.DKFZ* ; Begall, S. ; Frye, M.DKFZ* ; Odom, D. (Last author)DKFZ*
De novo genome assembly of Ansell's mole-rat (Fukomys anselli).
G3: Genes, genomes, genetics nn, nn (2025) [10.1093/g3journal/jkaf271]2025
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Jahn, A.DKFZ* ; Heining, C.DKFZ* ; Fröhling, S.DKFZ* ; Glimm, H.DKFZ* ; Schröck, E.DKFZ*
Targeted therapy in patients with genetic tumor syndromes.
Medizinische Genetik 37(4), 321 - 335 (2025) [10.1515/medgen-2025-2045]2025
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Floros, K. V. ; Fairchild, C. K. ; Li, J. ; Zhang, K. ; Roberts, J. L. ; Kurupi, R. ; Paudel, D. ; Xing, Y. ; Hu, B. ; Kraskauskiene, V. ; Hosseini, N. ; Shen, S. ; Inge, M. M. ; Smith-Fry, K. ; Li, L. ; Sotiriou, A.DKFZ* ; Dalton, K. M. ; Jose, A. ; Abdelfadiel, E. I. ; Hill, R. D. ; Slaughter, J. M. ; Shende, M. ; Lorenz, M. R. ; Tanaka, N. ; Kajino, T. ; Nelson, M. L. ; Hinojosa, M. R. ; Kehinde, V. A. ; Belvin, B. R. ; Sugiokto, F. G. ; Lai, Z. ; Dimopoulos, A. C. ; Boikos, S. A. ; Stamatouli, A. M. ; Lewis, J. P. ; Manjili, M. H. ; Ebi, H. ; Valerie, K. ; Li, R. ; Poklepovic, A. ; Koblinski, J. E. ; Siggers, T. ; Banito, A.DKFZ* ; Dozmorov, M. G. ; Jones, K. B. ; Radhakrishnan, S. K. ; Faber, A. C.
Targeting SUMOylation promotes cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma.
Nature Communications 16(1), 9761 (2025) [10.1038/s41467-025-64665-8]2025
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Journal Article (Other)
Loayza-Puch, F. (Last author)DKFZ*
Revealing the hidden coding potential of the human genome.
Nature reviews nn, nn (2025) [10.1038/s41580-025-00920-6]2025
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Drekolia, M.-K. ; Mettner, J. ; Wang, D. ; Delgado Lagos, F. ; Koch, C. ; Hecker, D. ; Eresch, J. ; Mao, Y. ; Bähr, M.DKFZ* ; Weichenhan, D.DKFZ* ; Cordero, J. ; Wittig, J. ; Zhang, B. ; Cui, H. ; Li, X. ; Oo, J. A. ; Weigert, A. ; Siragusa, M. ; Klatt, S. ; Fleming, I. ; Günther, S. ; Looso, M. ; Brandes, R. P. ; Langer, H. F. ; Papapetropoulos, A. ; Singhal, M. ; Schulz, M. H. ; Plass, C.DKFZ* ; Heineke, J. ; Dobreva, G. ; Hu, J. ; Bibli, S.-I.
Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation.
Cell metabolism nn, nn (2025) [10.1016/j.cmet.2025.10.003]2025
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Cloughesy, T. F. ; van den Bent, M. J. ; Touat, M. ; Blumenthal, D. T. ; Peters, K. B. ; Ellingson, B. M. ; Clarke, J. L. ; Mendez, J. ; Yust-Katz, S. ; Welsh, L. ; Mason, W. P. ; Ducray, F. ; Umemura, Y. ; Nabors, B. ; Holdhoff, M. ; Hottinger, A. F. ; Arakawa, Y. ; Sepulveda, J. M. ; Wick, W.DKFZ* ; Soffietti, R. ; Perry, J. ; Giglio, P. ; de la Fuente, M. ; Maher, E. ; Bottomley, A. ; Tron, A. E. ; Yi, D. ; Zhao, D. ; Pandya, S. S. ; Steelman, L. ; Hassan, I. ; Wen, P. Y. ; Mellinghoff, I. K. ; investigators, I. t. (Collaboration Author)
Vorasidenib in IDH1-mutant or IDH2-mutant low-grade glioma (INDIGO): secondary and exploratory endpoints from a randomised, double-blind, placebo-controlled, phase 3 trial.
The lancet / Oncology 26(12), 1665-1675 (2025) [10.1016/S1470-2045(25)00472-3]2025
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Cosenza, M. R. ; Gaiatto, A. ; Erarslan Uysal, B.DKFZ* ; Andrades, Á. ; Sautter, N. L. ; Simunovic, M. ; Jendrusch, M. A. ; Zumalave, S. ; Rausch, T. ; Halavatyi, A. ; Geissen, E.-M. ; Eigenmann, J. L. ; Weber, T. ; Hasenfeld, P. ; Benito, E. ; Stober, C. ; Cortes-Ciriano, I. ; Kulozik, A.DKFZ* ; Pepperkok, R. ; Korbel, J. (Last author)DKFZ*
Origins of chromosome instability unveiled by coupled imaging and genomics.
Nature nn, nn (2025) [10.1038/s41586-025-09632-5]2025
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Singh, G. ; Schmenger, T. ; Gonzalez-Sanchez, J. C. ; Kutkina, A. ; Bremec, N. ; Diwan, G. D. ; Mozas, P. ; López, C. ; Siebert, R. ; Sotillo, R.DKFZ* ; Russell, R. B.
Discriminating activating, deactivating and resistance variants in protein kinases.
Genome medicine 17(1), 133 (2025) [10.1186/s13073-025-01564-z]2025
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