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@ARTICLE{Voelker:167751,
author = {M. N. Voelker and O. Kraff and S. Goerke$^*$ and F. B. Laun
and J. Hanspach and K. J. Pine and P. Ehses and M. Zaiss and
A. Liebert and S. Straub$^*$ and K. Eckstein and S. Robinson
and A. N. Nagel and M. R. Stefanescu and A. Wollrab and S.
Klix and J. Felder and M. Hock and D. Bosch and N. Weiskopf
and O. Speck and M. E. Ladd$^*$ and H. H. Quick},
title = {{T}he {T}raveling {H}eads 2.0: {M}ulticenter
{R}eproducibility of {Q}uantitative {I}maging {M}ethods at 7
{T}esla.},
journal = {NeuroImage},
volume = {232},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {DKFZ-2021-00515},
pages = {117910},
year = {2021},
note = {2021 May 15;232:117910},
abstract = {This study evaluates inter-site and intra-site
reproducibility at ten different 7 T sites for quantitative
brain imaging.Two subjects - termed the 'traveling heads' -
were imaged at ten different 7 T sites with a harmonized
quantitative brain MR imaging protocol. In conjunction with
the system calibration, MP2RAGE, QSM, CEST and
multi-parametric mapping/relaxometry were
examined.Quantitative measurements with MP2RAGE showed very
high reproducibility across sites and subjects, and errors
were in concordance with previous results and other field
strengths. QSM had high inter-site reproducibility for
relevant subcortical volumes. CEST imaging revealed
systematic differences between the sites, but
reproducibility was comparable to results in the literature.
Relaxometry had also very high agreement between sites, but
due to the high sensitivity, differences caused by different
applications of the B1 calibration of the two RF coil types
used were observed.Our results show that quantitative brain
imaging can be performed with high reproducibility at 7 T
and with similar reliability as found at 3 T for multicenter
studies of the supratentorial brain.},
keywords = {Magnetic resonance imaging (Other) / multicenter (Other) /
quantitative imaging (Other) / reproducibility (Other) /
ultrahigh field (Other)},
cin = {E020},
ddc = {610},
cid = {I:(DE-He78)E020-20160331},
pnm = {315 - Bildgebung und Radioonkologie (POF4-315)},
pid = {G:(DE-HGF)POF4-315},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:33647497},
doi = {10.1016/j.neuroimage.2021.117910},
url = {https://inrepo02.dkfz.de/record/167751},
}