TY  - JOUR
AU  - Limongi, Tania
AU  - Brigo, Laura
AU  - Tirinato, Luca
AU  - Pagliari, Francesca
AU  - Gandin, Alessandro
AU  - Contessotto, Paolo
AU  - Giugni, Andrea
AU  - Brusatin, Giovanna
TI  - Three-dimensionally two-photon lithography realized vascular grafts.
JO  - Biomedical materials
VL  - 16
IS  - 3
SN  - 1748-605X
CY  - London
PB  - Inst. of Physics
M1  - DKFZ-2021-00622
SP  - 035013
PY  - 2021
AB  - Generation of artifical vascular grafts (TEVG) as blood vessel substitutes is a primary challenge in biomaterial and tissue engineering research. Ideally, these grafts should be able to recapitulate physiological and mechanical properties of natural vessels and guide the assembly of an endothelial cell lining to ensure hemo-compatibility. In this paper, we advance on this challenging task by designing and fabricating 3D vessel analogues by two-photon laser lithography using a synthetic photoresist. These scaffolds guarantee human endothelial cell adhesion and proliferation, and proper elastic behaviour to withstand the pressure exerted by blood flow.
KW  - 3D Fabrication (Other)
KW  - Microstructured scaffolds (Other)
KW  - Two-photon laser lithography (Other)
KW  - endothelial cells (Other)
KW  - vascular tissue engineering (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:33186926
DO  - DOI:10.1088/1748-605X/abca4b
UR  - https://inrepo02.dkfz.de/record/167901
ER  -