%0 Journal Article
%A Jansen, Jeannette
%A Knoll, Jan
%A Beyreuther, Elke
%A Pawelke, Jörg
%A Skuza, Raphael
%A Hanley, Rachel
%A Brons, Stephan
%A Pagliari, Francesca
%A Seco, Joao
%T Does FLASH deplete Oxygen? Experimental Evaluation for Photons, Protons and Carbon Ions.
%J Medical physics
%V 48
%N 7
%@ 2473-4209
%C College Park, Md.
%I AAPM
%M DKFZ-2021-01034
%P 3982-3990
%D 2021
%Z #EA:E041#LA:E041# /  2021 Jul;48(7):3982-3990
%X To investigate experimentally, if FLASH irradiation depletes oxygen within water for different radiation types such as photons, protons and carbon ions.This study presents measurements of the oxygen consumption in sealed, 3D printed water phantoms during irradiation with X-rays, protons and carbon ions at varying dose rates up to 340Gy/s. The oxygen measurement was performed using an optical sensor allowing for non-invasive measurements.Oxygen consumption in water only depends on dose, dose rate and linear energy transfer (LET) of the irradiation. The total amount of oxygen depleted per 10Gy was found to be 0.04
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:33948958
%R 10.1002/mp.14917
%U https://inrepo02.dkfz.de/record/168740