TY  - JOUR
AU  - Jansen, Jeannette
AU  - Knoll, Jan
AU  - Beyreuther, Elke
AU  - Pawelke, Jörg
AU  - Skuza, Raphael
AU  - Hanley, Rachel
AU  - Brons, Stephan
AU  - Pagliari, Francesca
AU  - Seco, Joao
TI  - Does FLASH deplete Oxygen? Experimental Evaluation for Photons, Protons and Carbon Ions.
JO  - Medical physics
VL  - 48
IS  - 7
SN  - 2473-4209
CY  - College Park, Md.
PB  - AAPM
M1  - DKFZ-2021-01034
SP  - 3982-3990
PY  - 2021
N1  - #EA:E041#LA:E041# /  2021 Jul;48(7):3982-3990
AB  - To investigate experimentally, if FLASH irradiation depletes oxygen within water for different radiation types such as photons, protons and carbon ions.This study presents measurements of the oxygen consumption in sealed, 3D printed water phantoms during irradiation with X-rays, protons and carbon ions at varying dose rates up to 340Gy/s. The oxygen measurement was performed using an optical sensor allowing for non-invasive measurements.Oxygen consumption in water only depends on dose, dose rate and linear energy transfer (LET) of the irradiation. The total amount of oxygen depleted per 10Gy was found to be 0.04
LB  - PUB:(DE-HGF)16
C6  - pmid:33948958
DO  - DOI:10.1002/mp.14917
UR  - https://inrepo02.dkfz.de/record/168740
ER  -