%0 Journal Article
%A Mayén, Ana-Lucia
%A Aglago, Elom K
%A Knaze, Viktoria
%A Cordova, Reynalda
%A Schalkwijk, Casper G
%A Wagner, Karl-Heinz
%A Aleksandrova, Krasimira
%A Fedirko, Veronika
%A Keski-Rahkonen, Pekka
%A Leitzmann, Michael F
%A Katzke, Verena
%A Srour, Bernard
%A Schulze, Matthias B
%A Masala, Giovanna
%A Krogh, Vittorio
%A Panico, Salvatore
%A Tumino, Rosario
%A Bueno-de-Mesquita, Bas
%A Brustad, Magritt
%A Agudo, Antonio
%A Chirlaque López, María Dolores
%A Amiano, Pilar
%A Ohlsson, Bodil
%A Ramne, Stina
%A Aune, Dagfinn
%A Weiderpass, Elisabete
%A Jenab, Mazda
%A Freisling, Heinz
%T Dietary intake of advanced glycation endproducts and risk of hepatobiliary cancers: A multinational cohort study.
%J International journal of cancer
%V 149
%N 4
%@ 0020-7136
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2021-01098
%P 854-864
%D 2021
%Z 2021 Apr 25;149(4):854-864
%X Advanced glycation endproducts (AGEs) may contribute to liver carcinogenesis because of their proinflammatory and prooxidative properties. Diet is a major source of AGEs, but there is sparse human evidence on the role of AGEs intake in liver cancer etiology. We examined the association between dietary AGEs and the risk of hepatobiliary cancers in the European Prospective Investigation into Cancer and Nutrition prospective cohort (n = 450 111). Dietary intake of three AGEs, Nε -[carboxymethyl]lysine (CML), Nε -[1-carboxyethyl]lysine (CEL) and Nδ -[5-hydro-5-methyl-4-imidazolon-2-yl]-ornithine (MG-H1), was estimated using country-specific dietary questionnaires linked to an AGEs database. Cause-specific hazard ratios (HR) and their 95
%K EPIC study (Other)
%K advanced glycation endproducts (Other)
%K bile duct cancers (Other)
%K gallbladder cancer (Other)
%K hepatocellular carcinoma (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:33899229
%R 10.1002/ijc.33612
%U https://inrepo02.dkfz.de/record/168847