Journal Article (Review Article)

DKFZ-2021-02166

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png How to get away with liver innate immunity? A viruses' tale.

Delphin, M. ; Desmares, M. ; Schuehle, S.DKFZ* ; Heikenwalder, M.DKFZ* ; Durantel, D. ; Faure-Dupuy, S. (Last author)DKFZ*

2021
Wiley-Blackwell Oxford

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Please use a persistent id in citations: doi:10.1111/liv.15054

Abstract: In their never-ending quest towards persistence within their host, hepatitis viruses have developed numerous ways to counteract the liver innate immunity. This review highlights the different and common mechanisms employed by these viruses to (i) establish in the liver (passive entry or active evasion from immune recognition) and (ii) actively inhibit the innate immune response (ie modulation of pattern recognition receptor expression and/or signalling pathways, modulation of interferon response and modulation of immune cells count or phenotype).

Keyword(s): MHC ; NF-κB ; PRR ; anti-inflammatory ; hepatic viruses ; innate immunity ; interferon ; liver ; pro-inflammatory

Note: #LA:F180# / 2021 Nov;41(11):2547-2559 / #DKFZ-MOST-Ca170#

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Contributing Institute(s):

1. Chronische Entzündung und Krebs (F180)

Research Program(s):

1. 316 - Infektionen, Entzündung und Krebs (POF4-316) (POF4-316)

Appears in the scientific report 2021

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Database coverage:
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Current Contents - Life Sciences ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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