%0 Journal Article
%A Pouyiourou, Maria
%A Wohlfromm, Timothy
%A Kraft, Bianca
%A Hielscher, Thomas
%A Stichel, Damian
%A von Deimling, Andreas
%A Delorme, Stefan
%A Endris, Volker
%A Neumann, Olaf
%A Stenzinger, Albrecht
%A Krämer, Alwin
%A Bochtler, Tilmann
%T Local ablative treatment with surgery and/or radiotherapy in single-site and oligometastatic carcinoma of unknown primary.
%J European journal of cancer
%V 157
%@ 0959-8049
%C Amsterdam [u.a.]
%I Elsevier
%M DKFZ-2021-02192
%P 179 - 189
%D 2021
%Z #EA:A360#LA:A360#
%X Single-site carcinoma of unknown primary (CUP) is recognised as a distinct favourable subtype in the European Society of Medical Oncology (ESMO) classification. There is broad consensus that these patients are candidates for local ablative treatment strategies with surgery and/or radiotherapy, but data on their outcomes are scarce.In this study, we have addressed the prospects of cure and prognostic factors in a retrospective cohort of 63 patients who were eligible for local treatment at our centre.Median event-free (EFS) and overall survival (OS) were 15.6 months and 52.5 months, respectively. Of 61 patients who received local treatment, 20 (32.8
%K CUP (cancer of unknown primary) (Other)
%K Copy number loss (Other)
%K Oligometastasis (Other)
%K Prognosis (Other)
%K Radiotherapy (Other)
%K Single metastatic deposit (Other)
%K Surgery (Other)
%K TP53 (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34521064
%R 10.1016/j.ejca.2021.08.019
%U https://inrepo02.dkfz.de/record/176959