TY  - JOUR
AU  - Pouyiourou, Maria
AU  - Wohlfromm, Timothy
AU  - Kraft, Bianca
AU  - Hielscher, Thomas
AU  - Stichel, Damian
AU  - von Deimling, Andreas
AU  - Delorme, Stefan
AU  - Endris, Volker
AU  - Neumann, Olaf
AU  - Stenzinger, Albrecht
AU  - Krämer, Alwin
AU  - Bochtler, Tilmann
TI  - Local ablative treatment with surgery and/or radiotherapy in single-site and oligometastatic carcinoma of unknown primary.
JO  - European journal of cancer
VL  - 157
SN  - 0959-8049
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DKFZ-2021-02192
SP  - 179 - 189
PY  - 2021
N1  - #EA:A360#LA:A360#
AB  - Single-site carcinoma of unknown primary (CUP) is recognised as a distinct favourable subtype in the European Society of Medical Oncology (ESMO) classification. There is broad consensus that these patients are candidates for local ablative treatment strategies with surgery and/or radiotherapy, but data on their outcomes are scarce.In this study, we have addressed the prospects of cure and prognostic factors in a retrospective cohort of 63 patients who were eligible for local treatment at our centre.Median event-free (EFS) and overall survival (OS) were 15.6 months and 52.5 months, respectively. Of 61 patients who received local treatment, 20 (32.8
KW  - CUP (cancer of unknown primary) (Other)
KW  - Copy number loss (Other)
KW  - Oligometastasis (Other)
KW  - Prognosis (Other)
KW  - Radiotherapy (Other)
KW  - Single metastatic deposit (Other)
KW  - Surgery (Other)
KW  - TP53 (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34521064
DO  - DOI:10.1016/j.ejca.2021.08.019
UR  - https://inrepo02.dkfz.de/record/176959
ER  -