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| Home > Publications database > Deuterium Metabolic Imaging in the human brain at 9.4 Tesla with high spatial and temporal resolution. > print |
| 001 | 177011 | ||
| 005 | 20240229133728.0 | ||
| 024 | 7 | _ | |a 10.1016/j.neuroimage.2021.118639 |2 doi |
| 024 | 7 | _ | |a pmid:34637905 |2 pmid |
| 024 | 7 | _ | |a 1053-8119 |2 ISSN |
| 024 | 7 | _ | |a 1095-9572 |2 ISSN |
| 024 | 7 | _ | |a altmetric:117376379 |2 altmetric |
| 037 | _ | _ | |a DKFZ-2021-02241 |
| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Ruhm, Loreen |b 0 |
| 245 | _ | _ | |a Deuterium Metabolic Imaging in the human brain at 9.4 Tesla with high spatial and temporal resolution. |
| 260 | _ | _ | |a Orlando, Fla. |c 2021 |b Academic Press |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a 2021 Dec 1;244:118639 |
| 520 | _ | _ | |a To present first highly spatially resolved deuterium metabolic imaging (DMI) measurements of the human brain acquired with a dedicated coil design and a fast chemical shift imaging (CSI) sequence at an ultrahigh field strength of B0 = 9.4 T. 2H metabolic measurements with a temporal resolution of 10 min enabled the investigation of the glucose metabolism in healthy human subjects.The study was performed with a double-tuned coil with 10 TxRx channels for 1H and 8TxRx/2Rx channels for 2H and an Ernst angle 3D CSI sequence with a nominal spatial resolution of 2.97 ml and a temporal resolution of 10 min.The metabolism of [6,6'-2H2]-labeled glucose due to the TCA cycle could be made visible in high resolution metabolite images of deuterated water, glucose and Glx over the entire human brain.X-nuclei MRSI as DMI can highly benefit from ultrahigh field strength enabling higher temporal and spatial resolutions. |
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| 650 | _ | 7 | |a 9.4 Tesla |2 Other |
| 650 | _ | 7 | |a DMI |2 Other |
| 650 | _ | 7 | |a TCA cycle |2 Other |
| 650 | _ | 7 | |a deuterium |2 Other |
| 650 | _ | 7 | |a human brain |2 Other |
| 650 | _ | 7 | |a oral glucose administration |2 Other |
| 700 | 1 | _ | |a Avdievich, Nikolai |b 1 |
| 700 | 1 | _ | |a Ziegs, Theresia |b 2 |
| 700 | 1 | _ | |a Nagel, Armin M |0 P:(DE-He78)054fd7a5195b75b11fbdc5c360276011 |b 3 |u dkfz |
| 700 | 1 | _ | |a De Feyter, Henk M |b 4 |
| 700 | 1 | _ | |a de Graaf, Robin A |b 5 |
| 700 | 1 | _ | |a Henning, Anke |b 6 |
| 773 | _ | _ | |a 10.1016/j.neuroimage.2021.118639 |g p. 118639 - |0 PERI:(DE-600)1471418-8 |p 118639 |t NeuroImage |v 244 |y 2021 |x 1053-8119 |
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| 910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 3 |6 P:(DE-He78)054fd7a5195b75b11fbdc5c360276011 |
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