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@ARTICLE{Gambichler:177084,
author = {T. Gambichler and S. Boms and L. Susok and H. Dickel and C.
Finis and N. Abu Rached and M. Barras and M. Stücker and D.
Kasakovski$^*$},
title = {{C}utaneous findings following {COVID}-19 vaccination:
{R}eview of world literature and own experience.},
journal = {Journal of the European Academy of Dermatology and
Venereology},
volume = {36},
number = {2},
issn = {0926-9959},
address = {Oxford [u.a.]},
publisher = {Wiley-Blackwell},
reportid = {DKFZ-2021-02290},
pages = {172-180},
year = {2022},
note = {2022 Feb;36(2):172-180},
abstract = {There is growing evidence that not only the novel
coronavirus disease (COVID-19) but also the COVID-19
vaccines can cause a variety of skin reactions. In this
review article, we provide a brief overview on cutaneous
findings that have been observed since the emerging mass
COVID-19 vaccination campaigns all over the world.
Unspecific injection site reactions very early occurring
after the vaccination are most frequent. Type I
hypersensitivity reactions (e.g., urticaria, angioedema,
anaphylaxis) likely due to allergy to ingredients may rarely
occur but can be severe. Type IV hypersensitivity reactions
may be observed, including delayed large local skin lesions
('COVID arm'), inflammatory reactions in dermal filler or
previous radiation sites or even old BCG scars, and more
commonly moribilliform and erythema multiforme-like rashes.
Autoimmune-mediated skin findings after COVID-19 vaccination
include leukocytoclastic vasculitis, lupus erythematosus,
and immune thrombocytopenia. Functional angiopathies
(chilblain-like lesions, erythromelalgia) may also be
observed. Pityriasis rosea-like rashes and reactivation of
herpes zoster have also been reported after COVID-19
vaccination. In conclusion, there are numerous cutaneous
reaction patterns that may occur following COVID-19
vaccination, whereby many of these skin findings are of
immunological/autoimmunological nature. Importantly,
molecular mimicry exists between SARS-CoV-2 (e.g., the
spike-protein sequences used to design the vaccines) and
human components and may thus explain some COVID-19
pathologies as well adverse skin reactions to COVID-19
vaccinations.},
subtyp = {Review Article},
keywords = {COVID-19 (Other) / SARS-CoV-2 (Other) / adverse events
(Other) / coronavirus (Other) / cutaneous reactions (Other)
/ molecular mimicry (Other) / side-effects (Other) / skin
(Other) / vaccination (Other) / vaccine (Other)},
cin = {A190},
ddc = {610},
cid = {I:(DE-He78)A190-20160331},
pnm = {311 - Zellbiologie und Tumorbiologie (POF4-311)},
pid = {G:(DE-HGF)POF4-311},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:34661927},
doi = {10.1111/jdv.17744},
url = {https://inrepo02.dkfz.de/record/177084},
}