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@ARTICLE{deVilliers:177416,
      author       = {E.-M. de Villiers$^*$ and H. zur Hausen$^*$},
      title        = {{B}ovine {M}eat and {M}ilk {F}actors ({BMMF}s): {T}heir
                      {P}roposed {R}ole in {C}ommon {H}uman {C}ancers and {T}ype 2
                      {D}iabetes {M}ellitus.},
      journal      = {Cancers},
      volume       = {13},
      number       = {21},
      issn         = {2072-6694},
      address      = {Basel},
      publisher    = {MDPI},
      reportid     = {DKFZ-2021-02508},
      pages        = {5407},
      year         = {2021},
      note         = {#EA:F200#LA:F200#},
      abstract     = {Exemplified by infections with bovine meat and milk factors
                      (BMMFs), this manuscript emphasizes the different
                      mechanistic aspects of infectious agents contributing to
                      human cancers by 'direct' or 'indirect' interactions. The
                      epidemiology of cancers linked to direct carcinogens (e.g.,
                      response to immunosuppression) differs from those cancers
                      linked with indirect infectious interactions. Cancers
                      induced by direct infectious carcinogens commonly increase
                      under immunosuppression, whereas the cancer risk by indirect
                      carcinogens is reduced. This influences their responses to
                      preventive and therapeutic interferences. In addition, we
                      discuss their role in colon, breast and prostate cancers and
                      type II diabetes mellitus. A brief discussion covers the
                      potential role of BMMF infections in acute myeloid
                      leukemia.},
      subtyp        = {Review Article},
      keywords     = {bovine meat and milk factors (BMMF) (Other) / chronic
                      zoonosis (Other) / indirect carcinogenesis (Other)},
      cin          = {F200},
      ddc          = {610},
      cid          = {I:(DE-He78)F200-20160331},
      pnm          = {316 - Infektionen, Entzündung und Krebs (POF4-316)},
      pid          = {G:(DE-HGF)POF4-316},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34771570},
      doi          = {10.3390/cancers13215407},
      url          = {https://inrepo02.dkfz.de/record/177416},
}