TY  - JOUR
AU  - Gredner, Thomas
AU  - Niedermaier, Tobias
AU  - Steindorf, Karen
AU  - Brenner, Hermann
AU  - Mons, Ute
TI  - Impact of reducing excess body weight and physical inactivity on cancer incidence in Germany from 2020 to 2050-a simulation model.
JO  - European journal of cancer
VL  - 160
SN  - 0014-2964
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DKFZ-2021-02799
SP  - 215-226
PY  - 2022
N1  - #EA:C070#LA:C070# / 2022 Jan;160:215-226
AB  - Excess body weight and physical inactivity are key cancer risk factors contributing substantially to the cancer burden in Germany. We aimed to estimate the numbers and proportions of future cancer cases prevented under different scenarios of reducing the prevalence of excess body weight and physical inactivity in Germany.Based on a macro-simulation approach calculating age-, sex-, and cancer-site specific potential impact fractions, we estimated for a 30-year study period (2020-2050) numbers and proportions of cancer cases prevented under different scenarios of reducing excess body weight (overweight and obesity) and increasing levels of physical activity in the German population.Estimates of the prevented cancer burden varied in the different scenarios. In the guideline exposure scenarios, in which the prevalence of excess body weight and insufficient levels of physical activity would be eliminated, 8.7
KW  - Cancer prevention (Other)
KW  - Obesity (Other)
KW  - Overweight (Other)
KW  - Physical inactivity (Other)
KW  - Potential impact fraction (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:34862080
DO  - DOI:10.1016/j.ejca.2021.10.026
UR  - https://inrepo02.dkfz.de/record/177758
ER  -