% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Gredner:177758,
      author       = {T. Gredner$^*$ and T. Niedermaier$^*$ and K. Steindorf$^*$
                      and H. Brenner$^*$ and U. Mons$^*$},
      title        = {{I}mpact of reducing excess body weight and physical
                      inactivity on cancer incidence in {G}ermany from 2020 to
                      2050-a simulation model.},
      journal      = {European journal of cancer},
      volume       = {160},
      issn         = {0014-2964},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2021-02799},
      pages        = {215-226},
      year         = {2022},
      note         = {#EA:C070#LA:C070# / 2022 Jan;160:215-226},
      abstract     = {Excess body weight and physical inactivity are key cancer
                      risk factors contributing substantially to the cancer burden
                      in Germany. We aimed to estimate the numbers and proportions
                      of future cancer cases prevented under different scenarios
                      of reducing the prevalence of excess body weight and
                      physical inactivity in Germany.Based on a macro-simulation
                      approach calculating age-, sex-, and cancer-site specific
                      potential impact fractions, we estimated for a 30-year study
                      period (2020-2050) numbers and proportions of cancer cases
                      prevented under different scenarios of reducing excess body
                      weight (overweight and obesity) and increasing levels of
                      physical activity in the German population.Estimates of the
                      prevented cancer burden varied in the different scenarios.
                      In the guideline exposure scenarios, in which the prevalence
                      of excess body weight and insufficient levels of physical
                      activity would be eliminated, $8.7\%$ (men: $10.1\%;$ women:
                      $7.8\%)$ of overweight/obesity-related cancer cases and
                      $2.4\%$ (men: $2.3\%;$ women: $2.4\%)$ of cancer cases
                      related to physical inactivity were estimated to be
                      prevented over a 30-year period. This translates to
                      approximately 662,000 (men: 304,000; women: 358,000) and
                      129,000 (men: 42,000; women: 87,000) prevented cancer cases,
                      respectively.Our results illustrate that a substantial
                      number of future cancer cases could be prevented in the
                      German population by reducing excess body weight and
                      physical inactivity.},
      keywords     = {Cancer prevention (Other) / Obesity (Other) / Overweight
                      (Other) / Physical inactivity (Other) / Potential impact
                      fraction (Other)},
      cin          = {C070 / C110 / C120 / HD01 / M050},
      ddc          = {610},
      cid          = {I:(DE-He78)C070-20160331 / I:(DE-He78)C110-20160331 /
                      I:(DE-He78)C120-20160331 / I:(DE-He78)HD01-20160331 /
                      I:(DE-He78)M050-20160331},
      pnm          = {313 - Krebsrisikofaktoren und Prävention (POF4-313)},
      pid          = {G:(DE-HGF)POF4-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34862080},
      doi          = {10.1016/j.ejca.2021.10.026},
      url          = {https://inrepo02.dkfz.de/record/177758},
}