Journal Article (Review Article)

DKFZ-2021-02930

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Lessons learned from the INHANCE consortium: An overview of recent results on head and neck cancer.

Bravi, F. ; Lee, Y. A. ; Hashibe, M. ; Boffetta, P. ; Conway, D. I. ; Ferraroni, M. ; La Vecchia, C. ; Edefonti, V. ; investigators, I. C. (Collaboration Author) ; Agudo, A. ; Ahrens, W. ; Benhamou, S. ; Boccia, S. ; Brennan, P. ; Brenner, H.DKFZ* ; Cadoni, G. ; Canova, C. ; Chen, C. ; Chuang, S.-C. ; Curado, M. P. ; Dal Maso, L. ; Daudt, A. W. ; D'Souza, G. ; Fabianova, E. ; Fernandez, L. ; Franceschi, S. ; Garavello, W. ; Gillison, M. ; Gross, N. D. ; Hayes, R. B. ; Healy, C. ; Herrero, R. ; Holcatova, I. ; Kelsey, K. ; Kjaerheim, K. ; Koifman, R. ; Lagiou, P. ; Lazarus, P. ; Levi, F. ; Li, G. ; Lissowska, J. ; Luce, D. ; Macfarlane, G. J. ; Mates, D. ; Matsuo, K. ; McClean, M. ; Menezes, A. ; Menvielle, G. ; Morgenstern, H. ; Moyses, R. A. ; Moysich, K. ; Muscat, J. ; Negri, E. ; Olshan, A. F. ; Pandics, T. ; Polesel, J. ; Purdue, M. P. ; Radoï, L. ; Ramroth, H. ; Richiardi, L. ; Schantz, S. ; Schwartz, S. M. ; Serraino, D. ; Shangina, O. ; Smith, E. ; Sturgis, E. M. ; Świątkowska, B. ; Thomson, P. ; Toporcov, T. N. ; Vaughan, T. L. ; Vilensky, M. ; Winn, D. M. ; Wunsch-Filho, V. ; Yu, G.-P. ; Zevallos, J. P. ; Zhang, Z.-F. ; Zheng, T. ; Znaor, A.

2021
Wiley-Blackwell Oxford [u.a.]

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Please use a persistent id in citations: doi:10.1111/odi.13502

Abstract: To summarize the latest evidence on head and neck cancer epidemiology from the International Head and Neck Cancer Epidemiology (INHANCE) consortium.INHANCE was established in 2004 to elucidate the etiology of head and neck cancer through pooled analyses of individual-level data on a large scale. We summarize results from recent INHANCE-based publications updating our 2015 overview.Seventeen papers were published between 2015 and May 2020. These studies further define the nature of risks associated with tobacco and alcohol, and occupational exposures on head and neck cancer. The beneficial effects on incidence of head and neck cancer were identified for good oral health, endogenous and exogenous hormonal factors, and selected aspects of diet related to fruit and vegetables. INHANCE has begun to develop risk prediction models and to pool follow-up data on their studies, finding that ~30% of cases had cancer recurrence and 9% second primary cancers, with overall- and disease-specific 5-year-survival of 51% and 57%, respectively.The number and importance of INHANCE scientific findings provides further evidence of the advantages of large-scale internationally collaborative projects and will support the development of prevention strategies.

Keyword(s): Case-Control Studies (MeSH) ; Head and Neck Neoplasms: epidemiology (MeSH) ; Humans (MeSH) ; Neoplasm Recurrence, Local (MeSH) ; Risk Factors (MeSH) ; Tobacco Use (MeSH) ; INHANCE ; head and neck cancer ; laryngeal cancer ; oral cavity cancer ; pooled analysis ; prognostic factors ; risk factors

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Contributing Institute(s):

1. C070 Klinische Epidemiologie und Alternf. (C070)

Research Program(s):

1. 313 - Krebsrisikofaktoren und Prävention (POF4-313) (POF4-313)

Appears in the scientific report 2021

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Database coverage:
; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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