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@ARTICLE{Ryzhova:178293,
author = {M. V. Ryzhova and E. N. Telysheva and E. G. Shaikhaev and
D. V. Starovoitov and A. O. Kotelnikova and S. A. Galstyan
and K. Okonechnikov$^*$},
title = {{S}ovremennye diagnosticheskie vozmozhnosti molekulyarnogo
issledovaniya opukholei mozga v {T}sentre neirokhirurgii im.
akad. {N}.{N}. {B}urdenko.},
journal = {Zurnal voprosy nejrochirurgii imeni N.N. Burdenko},
volume = {85},
number = {6},
issn = {0042-8817},
address = {Moskva},
publisher = {Nakl. Medicina},
reportid = {DKFZ-2021-03240},
pages = {98},
year = {2021},
note = {#LA:B062#},
abstract = {DnA methylation has recently been accepted as the most
reliable and effective method of diagnosing central nervous
system (CNS) tumors. Healthy organs and tumors of different
localizations have their own unique methylation structure.
Determination of total tumor DNA methylome is the detection
of all methylated nucleotides in a tumor. The 'gold
standard' for analyzing the methylation state of individual
cytosines is bisulfite conversion, in which unmethylated
cytosines are converted to uracils and read as thymines,
while methylated cytosines are protected from conversion.},
keywords = {Brain Neoplasms: genetics / DNA: metabolism / DNA
Methylation / Humans / DNA methylation (Other) / EPIC array
(Other) / Illumina Infinium HumanMethylation850 BeadChip
(Other) / DNA (NLM Chemicals)},
cin = {B062},
ddc = {610},
cid = {I:(DE-He78)B062-20160331},
pnm = {312 - Funktionelle und strukturelle Genomforschung
(POF4-312)},
pid = {G:(DE-HGF)POF4-312},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:34951766},
doi = {10.17116/neiro20218506198},
url = {https://inrepo02.dkfz.de/record/178293},
}